Results 51 to 60 of about 846,956 (260)
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Dissolved organic carbon (DOC) represents the most readily available and crucial carbon source for soil microorganisms, influencing their community structure, nutrient cycling, and metabolic functions.
Xiaoyu Han +6 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Biochar is a carbon-rich product obtained by pyrolyzing biomass under oxygen-limited conditions and has a wide range of potential for environmental applications.
Yaru Li +5 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Spatial differences of dissolved organic matter composition and humification in an artificial lake
The depth-dependent dynamics of dissolved organic matter (DOM) structure and humification in an artificial lake limits the understanding of lake eutrophication and carbon cycling. Using fluorescence regional integration (FRI) and parallel factor analysis
Jin Zhang, Jiajia Tan, Yingjie Wang
doaj +1 more source
Performance Analysis of Parallel Pollard's Rho Factoring Algorithm
Integer factorization is one of the vital algorithms discussed as a part of analysis of any black-box cipher suites where the cipher algorithm is based on number theory. The origin of the problem is from Discrete Logarithmic Problem which appears under the analysis of the cryptographic algorithms as seen by a cryptanalyst.
Anjan K Koundinya +6 more
openaire +1 more source
Blind Spectral Decomposition of Single-Cell Fluorescence by Parallel Factor Analysis [PDF]
Simultaneous measurement of multiple signaling molecules is essential to investigate their relations and interactions in living cells. Although a wide variety of fluorescent probes are currently available, the number of probes that can be applied simultaneously is often limited by the overlaps among their fluorescence spectra.
Shirakawa, Hideki, Miyazaki, Shunichi
openaire +2 more sources

