Results 81 to 90 of about 4,060,865 (318)
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Haplotype tagging reveals parallel formation of hybrid races in two butterfly species
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance A defining goal in genetics is linking variation in DNA sequence to trait evolution between populations and, ultimately, species. Genome sequencing efficiently captures such variation but typically in millions of tiny fragments that omit ...
J. Meier +13 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Historical Crisis and Cosmic Crisis in Mark 13 and Lucan's _Civil War_
Tyndale Bulletin, 1997 This article suggests that the association of the fall of Jerusalem and the consummation of the age in Mark 13 finds a parallel in the linkage of the collapse of the Roman Republic and the collapse of the cosmos in Lucan’s Civil War.
Edward Adams
doaj +1 more source
, 1996 Parallel Computational Fluid Dynamics(CFD) is an internationally recognised fast-growing field. Since 1989, the number of participants attending Parallel CFD Conferences has doubled. In order to keep track of current global developments, the Parallel CFD
Parallel CFD Conference(1995 :Pasadena, Calif.) +1 more
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Kinematic analysis of a single-loop reconfigurable 7R mechanism with multiple operation modes [PDF]
, 2014 This paper presents a novel one-degree-of-freedom (1-DOF) single-loop reconfigurable 7R mechanism with multiple operation modes (SLR7RMMOM), composed of seven revolute (R) joints, via adding a revolute joint to the overconstrained Sarrus linkage.
Chablat, Damien +4 more
core +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Regression analysis under probabilistic multi-linkage
, 2011 Linkage errors can occur when probability-based methods are used to link records from two distinct data sets corresponding to the same target population.
Gunky Kim (20124087) +1 more
core +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source