Results 71 to 80 of about 4,060,865 (318)
Generalized Linkage Construction for Constant-Dimension Codes [PDF]
A constant-dimension code (CDC) is a set of subspaces of constant dimension in a common vector space with upper bounded pairwise intersection. We improve and generalize two constructions for CDCs, the improved linkage construction and the parallel ...
Daniel Heinlein
semanticscholar +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
(E)-N′-(2-Thienylmethylidene)-p-toluenesulfonohydrazide
The S—N(H)—N=C linkage in the title molecule, C12H12N2O2S2, is non-planar [torsion angle = 15.5 (1)°] as the amino N atom is pyramidally coordinated.
Abdullah M. Asiri +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
(E)-N′-(9-Anthrylmethylidene)-p-toluenesulfonohydrazide
The S—N(H)—N=C linkage in the title molecule, C22H18N2O2S, is non-planar [torsion angle = 30.6 (1)°] as the amino N atom is pyramidally coordinated.
Abdullah M. Asiri +2 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
A mixed indium–iron lithium diphosphate, In0.51Fe0.49LiP2O7
The structure of In0.51Fe0.49LiP2O7 consists of a three-dimensional network constructed from (InIII/FeIII)O6 octahedra and P2O7 groups. Each MIIIO6 octahedron is linked to six PO4 tetrahedra belonging to five different P2O7 groups and shares two corners ...
Hafid Zouihri +3 more
doaj +1 more source
Cichlid fishes are an excellent model system for studying speciation and the formation of adaptive radiations because of their tremendous species richness and astonishing phenotypic diversity.
H. Recknagel, K. Elmer, A. Meyer
semanticscholar +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source

