Results 61 to 70 of about 4,060,865 (318)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Quality of record linkage in a highly automated cancer registry that relies on encrypted identity data

GMS Medizinische Informatik, Biometrie und Epidemiologie, 2016
Objectives: In the absence of unique ID numbers, cancer and other registries in Germany and elsewhere rely on identity data to link records pertaining to the same patient. These data are often encrypted to ensure privacy.
Schmidtmann, Irene, Sariyar, Murat, Borg, Andreas, Gerold-Ay, Aslihan, Heidinger, Oliver, Hense, Hans-Werner, Krieg, Volker, Hammer, Gaël Paul   +7 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The serial-parallel dilemma: A case study in a linkage of theory and method [PDF]

Psychonomic Bulletin & Review, 2004
The question as to whether humans perceive, remember, or cognize psychological items simultaneously (i.e., in parallel) or sequentially (i.e., serially) has been of interest to philosophers and psychologists since at least the 19th century. The advent of the information-processing approach to cognition in the 1960s reopened the inquiry, initiating a ...
James T, Townsend, Michael J, Wenger
openaire   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

A Parallel Multi-Party Privacy-Preserving Record Linkage Method Based on a Consortium Blockchain

Mathematics
Privacy-preserving record linkage (PPRL) is the process of linking records from various data sources, ensuring that matching records for the same entity are shared among parties while not disclosing other sensitive data.
Shumin Han, Zikang Wang, Dengrong Shen, Chuang Wang   +3 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

A novel prosthetic knee joint with a parallel spring and damping mechanism

International Journal of Advanced Robotic Systems, 2016
Prosthetic knee joint (PKJ) is an important apparatus for trans-femoral amputees to regain walking ability. This study has two objectives: (1) to design a high performance and low-cost passive PKJ and (2) to evaluate the performance of the PKJ.
Huiqun Fu, Xiufeng Zhang, Xitai Wang, Rong Yang, Jian Li, Li Wang, Ning Zhang, Guanglin Li, Tao Liu, Bingfei Fan, Yoshio Inoue   +10 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Topological Analysis of a Novel Compact Omnidirectional Three-Legged Robot with Parallel Hip Structures Regarding Locomotion Capability and Load Distribution

Robotics, 2021
In this study, a novel design for a compact, lightweight, agile, omnidirectional three-legged robot involving legs with four degrees of freedom, utilizing an spherical parallel mechanism with an additional non-redundant central support joint for the ...
David Feller, Christian Siemers
doaj   +1 more source