Results 61 to 70 of about 110,234 (214)
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
RbZnFe(PO4)2: synthesis and crystal structure
Acta Crystallographica Section E: Crystallographic Communications, 2016 A new iron phosphate, rubidium zinc iron(III) phosphate, RbZnFe(PO4)2, has been synthesized as single crystals by the flux method. This compound is isostructural to the previously reported KCoAl(PO4)2 [Chen et al. (1997). Acta Cryst. C53,1754–1756].
Abdessalem Badri, Mongi Ben Amara
doaj +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Research of the Linkage Point Trajectory Curvature and Design of the Related Mechanism
Jixie chuandong, 2017 The linkage point trajectory curvature theory on the existing literature is summarized and improved. Another method determining the linkage point trajectory curvature center by the absolute and relative instantaneous center is working out.
Wang Yundi +3 more
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Design and Calibration of a New 6 DOF Haptic Device
Sensors, 2015 For many applications such as tele-operational robots and interactions with virtual environments, it is better to have performance with force feedback than without. Haptic devices are force reflecting interfaces.
Huanhuan Qin +4 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Optimization of Watt's Six-bar Linkage to Generate Straight and Parallel Leg Motion
International Journal of Advanced Robotic Systems, 2008 This paper considers optimal synthesis of a special type of four-bar linkages. Combination of this optimal four-bar linkage with on of it's cognates and elimination of two redundant cognates will result in a Watt's six-bar mechanism, which generates ...
Saeed Akbarnejad, Hamid Mehdigholi
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Design and Research Co-Simulation Platform of Navigation and Dynamics on Planetary Rovers
Xibei Gongye Daxue Xuebao, 2019 The overall design idea of simulation platform of the planetary rover coupling navigation and dynamics is proposed to address the dilemma faced in the design of a navigation control system for Mars and other planetary exploration tasks.
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