Results 161 to 170 of about 13,001,808 (334)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Parallel Mechanisms. Micro-hand Based on the Parallel Mechanisms.

Journal of the Japan Society for Precision Engineering, 1997
Tatsuo ARAI, Tamio TANIKAWA
openaire   +2 more sources

Parallel Mechanisms. Parallel Mechanism Drilling Machine (three-degree-of-freedom).

Journal of the Japan Society for Precision Engineering, 1997
Eiichi MORI, Hideo IWABUCHI
openaire   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Design and DOF Analysis of a Novel Compliant Parallel Mechanism for Large Load. [PDF]

Sensors (Basel), 2019
Wu X, Lu Y, Duan X, Zhang D, Deng W.
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Development of a Bayesian Network-Based Parallel Mechanism for Lower Limb Gait Rehabilitation. [PDF]

Biomimetics (Basel)
Ma H, Bao Y, Jia C, Chen G, Lan J, Shi M, Li H, Guo Q, Guan L, Li S, Zhang P.   +10 more
europepmc   +1 more source

Parallel Mechanisms. Wire Driven Parallel Mechanisms.

Journal of the Japan Society for Precision Engineering, 1997
openaire   +2 more sources

Parallel Mechanism

Journal of the Japan Society for Precision Engineering, 2005
openaire   +2 more sources