Results 71 to 80 of about 809,085 (214)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

A Miniature Soft Sensor with Origami-Inspired Self-Folding Parallel Mechanism. [PDF]

Micromachines (Basel), 2022
Shi Y, Wang G, Sun W, Ya Y, Liu S, Fang J, Yuan F, Duo Y, Wen L.   +8 more
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Prediction of the RNA Tertiary Structure Based on a Random Sampling Strategy and Parallel Mechanism. [PDF]

Front Genet, 2021
Liu Z, Yang Y, Li D, Lv X, Chen X, Dai Q.   +5 more
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Novel Kinematically Redundant (3+1)-DOF Delta-Type Parallel Mechanisms

Robotics
Although parallel mechanisms are used in various fields, their application is often limited by singularities and a restricted workspace. Kinematic redundancy is a promising approach for mitigating these issues while also extending the functionality of ...
Pavel Laryushkin, Anton Antonov, Egor Ispolov, Maria Goncharova, Ayşe Ceren Aydil   +4 more
doaj   +1 more source

Development of 6 DOF Displacement Sensor Using RUS Parallel Mechanism. [PDF]

Sensors (Basel), 2021
Kim D, Choi S, Yun D.
europepmc   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Workspace and Singularity Analysis of 4-DOF 3R1T Parallel Mechanism with a Circular Rail

Robotics
Limited workspace and singularities are major challenges for parallel mechanisms. This article addresses these issues for a 4-DOF 1-SPS/3-RRRRR parallel mechanism with a circular rail, proposed in our prior work. The mechanism has a 3R1T motion type with
Pavel Laryushkin, Ilya Brem, Alexey Fomin, Anton Antonov   +3 more
doaj   +1 more source

Workspace and Orientation Analysis of a Parallel Structure for Robotic Fingers

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2011
This paper investigates the workspace and the orientation capability of robotic fingers with a five-bar linkage and its variance defined by the parameter of a base link.
Wei YAO, Jian S DAI
doaj   +1 more source