Results 31 to 40 of about 7,215 (215)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Unified Singularity Modeling and Reconfiguration of 3rT Metamorphic Parallel Mechanisms with Parallel Constraint Screws

Advances in Mechanical Engineering, 2015
This paper presents a unified singularity modeling and reconfiguration analysis of variable topologies of a class of metamorphic parallel mechanisms with parallel constraint screws.
Yufeng Zhuang, Dongming Gan
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Type Synthesis of Fully-Decoupled Three-Rotational and One-Translational Parallel Mechanisms

International Journal of Advanced Robotic Systems, 2016
Based on screw theory and the principle of one- leg driving by an independent motor, a methodology for the structural synthesis of fully-decoupled three-rotational and one-translational (3R1T) parallel mechanisms is proposed by analysing the ...
Yi Cao, Hai Chen, Youlei Qin, Kai Liu, Shuyi Ge, Jingyuan Zhu, Kun Wang, Jinghu Yu, Weixi Ji, Hui Zhou   +9 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Centimeter‐Scale Magneto‐Reconfigurable Parallel Robots: A Grassmann Line Geometry Synthesis Framework for Multitask Adaptation Using Magneto‐Connected Part Library

Advanced Intelligent Systems
The development of centimeter‐scale reconfigurable parallel robots is critical for applications requiring precise, adaptive, and space‐constrained operations across bench‐top automation and minimally invasive systems. However, existing platforms struggle
Yunong Li, Bin Zhu, Wenchao Yue, Zhiwei Fang, Xiao Xiao, Hongliang Ren   +5 more
doaj   +1 more source

Type Synthesis of 4-DOF Non-Overconstrained Parallel Mechanisms with Symmetrical Structures

Machines, 2022
This paper presents the type synthesis of 4-DOF non-overconstrained parallel mechanisms (PMs) with symmetrical structures. A special topological structure that includes two intermediate platforms and one moving platform is employed. Constraint conditions
Wei Ye, Qinchuan Li, Xinxue Chai
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Parallel mechanisms with adjustable link parameters

Proceedings. 2000 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS 2000) (Cat. No.00CH37113), 2002
There has been always a workspace problem with parallel mechanisms. This paper discusses the workspace of the parallel mechanisms and its enlargement by adjusting their link parameters. The basic idea is to cover a whole required range of workspace with small pieces of one.
Arai, Tatsuo, Koseki, Yoshihiko, Takayama, Kazunari, Inoue, Kenji, Mae, Yasushi   +4 more
openaire   +2 more sources