Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Parallel implementation of stochastic simulation for large-scale cellular processes [PDF]
, 2005 Experimental and theoretical studies have shown the importance of stochastic processes in genetic regulatory networks and cellular processes. Cellular networks and genetic circuits often involve small numbers of key proteins such as transcriptional ...
Kevin Burrage +6 more
core +1 more source
PARALLELIZED NUMERICAL CODE FOR DERIVATION OF HEAT TRANSFER COEFFICIENT FROM EXPERIMENTAL DATA
TASK Quarterly, 2015 An application of parallel computation capabilities in the MATLAB language for the analysis of experimental data concerning the heat transfer coefficient on ribbed walls is presented in this paper.
JANUSZ TELEGA +3 more
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Robust parallel eigenvector computation for the non-symmetric eigenvalue problem
, 2020 A standard approach for computing eigenvectors of a non-symmetric matrix reduced to real Schur form relies on a variant of backward substitution. Backward substitution is prone to overflow.
Schwarz, Angelika Beatrix, +2 more
core +1 more source
The development of laser-plasma interaction program LAP3D on thousands of processors
AIP Advances, 2015 Modeling laser-plasma interaction (LPI) processes in real-size experiments scale is recognized as a challenging task. For explorering the influence of various instabilities in LPI processes, a three-dimensional laser and plasma code (LAP3D) has been ...
Xiaoyan Hu +5 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
A Java-based parallel platform for the implementation of evolutionary computation for engineering applications [PDF]
, 2003 As computers continually improve in performance and decrease in manufacturing cost, distributed systems consisting of multiple computers implemented as parallel computation platforms have become viable for engineering applications which demand intensive ...
Wong, K.W. +3 more
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
SPRINT: A new parallel framework for R [PDF]
, 2008 25.03.14 KB. Ok to add published version to spiral, OA paperBACKGROUND:Microarray analysis allows the simultaneous measurement of thousands to millions of genes or sequences across tens to thousands of different samples.
Mewissen, Muriel +8 more
core +1 more source