Results 121 to 130 of about 3,604,803 (308)
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
EPJ Web of Conferences, 2014 The work is devoted to 3D and 2D parallel numerical computation of pressure and velocity fields around an elastically supported airfoil self-oscillating due to interaction with the airflow.
Řidký Václav, Šidlof Petr
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Scalable data abstractions for distributed parallel computations [PDF]
, 2012 The ability to express a program as a hierarchical composition of parts is an essential tool in managing the complexity of software and a key abstraction this provides is to separate the representation of data from the computation.
Hollis, Simon J. +2 more
core
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Mechanical Engineering JournalIn this study, a parallel three-scale homogenization analysis simulator that accounts for macro-, meso-, and micro-scale structures was developed for the carbon-fiber-reinforced plastics (CFRPs) used in high-pressure hydrogen storage vessels manufactured
Naoki MORITA +5 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Calcolo: A Quarterly on Numerical Analysis and Theory of Computation Vol 60
, 2023 Under the direction of the Institute for Informatics and Telematics in Pisa, Calcolo publishes original contributions on numerical analysis and its applications, and on the theory of computation.
N Guglielmi +3 more
core
Sustainable Energy ResearchUltra-high-voltage (UHV) autotransformers are widely employed in long-distance power transmission systems. Their operation involves complex energy conversion and coupling mechanisms, including high-intensity magnetic induction energy and strong induced ...
E. Tianlong +4 more
doaj +1 more source