Results 61 to 70 of about 2,064,930 (283)

Parallel Processing For Schema Evolution in Database Systems [PDF]

open access: yes, 2013
A thesis submitted to the University of London in partial fulfillment of the requirements of the degree of Doctor of ...
Labib, Gamal Ali Mohamed
core  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Multistructure-Based Collaborative Online Distillation

open access: yesEntropy, 2019
Recently, deep learning has achieved state-of-the-art performance in more aspects than traditional shallow architecture-based machine-learning methods. However, in order to achieve higher accuracy, it is usually necessary to extend the network depth or ...
Liang Gao   +5 more
doaj   +1 more source

Live Demonstration: Multiplexing AER Asynchronous Channels over LVDS Links with Flow-Control and Clock- Correction for Scalable Neuromorphic Systems [PDF]

open access: yes, 2017
In this live demonstration we exploit the use of a serial link for fast asynchronous communication in massively parallel processing platforms connected to a DVS for realtime implementation of bio-inspired vision processing on spiking neural ...
Furber, Steve B.   +8 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Transductive Nonnegative Matrix Tri-Factorization

open access: yesIEEE Access, 2020
Nonnegative matrix factorization (NMF) decomposes a nonnegative matrix into the product of two lower-rank nonnegative matrices. Since NMF learns parts-based representation, it has been widely used as a feature learning component in many fields.
Xiao Teng   +4 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Speeding up parallel processing [PDF]

open access: yes
In 1967 Amdahl expressed doubts about the ultimate utility of multiprocessors. The formulation, now called Amdahl's law, became part of the computing folklore and has inspired much skepticism about the ability of the current generation of massively ...
Denning, Peter J.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Enhancing Stock Price Trend Prediction via a Time-Sensitive Data Augmentation Method

open access: yesComplexity, 2020
Stock trend prediction refers to predicting future price trend of stocks for seeking profit maximum of stock investment. Although it has aroused broad attention in stock markets, it is still a tough task not only because the stock markets are complex and
Xiao Teng   +4 more
doaj   +1 more source

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