Results 111 to 120 of about 677,509 (341)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

A tool for automatic parallelization of affine programs for systems with shared and distributed memory

open access: yesРоссийский технологический журнал, 2019
Effective programming of parallel architectures has always been a challenge, and it is especially complicated with their modern diversity. The task of automatic parallelization of program code was formulated from the moment of the appearance of the first
Sh. G. Magomedov, A. S. Lebedev
doaj   +1 more source

FastFlow tutorial

open access: yes, 2012
FastFlow is a structured parallel programming framework targeting shared memory multicores. Its layered design and the optimized implementation of the communication mechanisms used to implement the FastFlow streaming networks provided to the application ...
Aldinucci, Marco   +2 more
core  

Verification of Program Parallelization [PDF]

open access: yes, 2018
This thesis presents a set of verification techniques based on permission-based separation logic to reason about the data race freedom and functional correctness of program parallelizations. Our reasoning techniques address different forms of high-level and low-level parallelization.
openaire   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Parallel Program Analysis via Range Splitting [PDF]

open access: hybrid, 2023
Jan Haltermann   +3 more
openalex   +1 more source

Cache-aware Parallel Programming for Manycore Processors

open access: yes, 2013
With rapidly evolving technology, multicore and manycore processors have emerged as promising architectures to benefit from increasing transistor numbers.
Tousimojarad, Ashkan   +1 more
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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