Results 111 to 120 of about 103,699 (311)
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
FATCOP: A Fault Tolerant Condor-PVM Mixed Integer Programming Solver
, 1999 We describe FATCOP, a new parallel mixed integer program solver written in PVM. The implementation uses the Condor resource management system to provide a virtual machine composed of otherwise idle computers.
Chen, Qun, Ferris, Michael
core
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Parallel Composition and Bulk Synchronous Parallel Functional Programming
, 2001 The work described here is part of our research program to investigate new paradigms for declarative parallel programming through special interpretations of standard semantics. Our approach is a purely functional approach to programming of BSP algorithms
Parallel Composition And +1 more
core
The parallel programming of landing position in saccadic eye movement sequences. [PDF]
J Vis, 2020 McSorley E, Gilchrist ID, McCloy R.
europepmc +1 more source
Parallelism in Constraint Programming. [PDF]
, 2011 Writing efficient parallel programs is the biggest challenge of the software industry for the foreseeable future. We are currently in a time when parallel computers are the norm, not the exception. Soon, parallel processors will be standard even in cell phones.
openaire +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Programming Future Parallel Architectures with Haskell and Intel ArBB
, 2011 New parallel architectures, such as Cell, Intel MIC,GPUs, and tiled architectures, enable high performance but areoften hard to program. What is needed is a bridge betweenhigh-level programming models where programmers are mostproductive and modern ...
Svensson, Joel Bo,, Newton, Ryan
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Design patterns percolating to parallel programming framework implementation
, 2014 Structured parallel programming is recognised as a viable and effective means of tackling parallel programming problems. Recently, a set of simple and powerful parallel building blocks ( RISC- pb2l RISC - pb 2 l ) has been proposed to support modelling ...
Kilpatrick P. +4 more
core +1 more source