Results 81 to 90 of about 1,785,585 (297)

Oregon Coastal Salmon Restoration Initiative: Oregon's plan for conservation and restoration of anadromous salmonids in coastal river basins : draft

, 1996
[Main report] -- Executive summary -- attachment I. Management measures, books 1-4 -- attachment II. Science Team information and products -- attachment III. Information related to habitat restoration projects -- attachment IV.

core  

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

THEIOI AUTOKRATORES. A Fragment of an Honorary Inscription from the Smintheion

Gephyra
This article presents a fragmentary inscribed slab discovered in the sanctuary of Apollo Smintheus in 2009. The author proposes a restoration for this fragmentary inscription in the article, by comparing it with parallel epigraphic examples from Asia ...
Tolga Özhan
doaj   +1 more source

Conservation-Restoration paradigm shift after disaster: the Graphic Documents case study

Conservar Património, 2017
With this paper we draw attention to the role of the disaster, leading to profound changes, to the paradigm shift in the intervention of conservation and restoration of graphic documents, based on the study of case studies from the two main disaster ...
Maria da Conceição Lopes Casanova
doaj   +1 more source

Restoration of Degraded Images Using Pupil-Size Diversity Technology With Stochastic Parallel Gradient Descent Algorithm

IEEE Photonics Journal, 2016
The performance of imaging systems is inevitably degraded by aberrations of optical systems. Furthermore, images detected by long-distance imaging schemes also suffer blurring induced by atmospheric turbulence.
Zongliang Xie, Haotong Ma, Bo Qi, Ge Ren, Yufeng Tan, Bi He, Hengliang Zeng, Chuan Jiang   +7 more
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Second-Order Cone Programming Algorithm for Collaborative Optimization of Load Restoration Integrated with Electric Vehicles

Energies
In response to the influence of extreme disasters, damage to distribution lines and user outages, a parallel implementation strategy is proposed for emergency repair of disaster-damaged distribution networks and rapid restoration of power supply for ...
Dexiang Li, Ling Li, Huijie Sun, Milu Zhou, Zhijian Du, Jiekang Wu   +5 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source