Results 61 to 70 of about 1,770,360 (244)

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

A Dual-Branch Parallel Network for Speech Enhancement and Restoration

Computer Speech & Language
Accepted for publication in Computer Speech & Language (2026).
Da-Hee Yang, Dail Kim, Joon-Hyuk Chang, Jeonghwan Choi, Han-Gil Moon   +4 more
openaire   +2 more sources

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Transient feasibility assessment and enhancement of resilience-oriented distribution grid restoration using parallel simulations

The Journal of Engineering, 2019
In recent years, major power outages caused by extreme natural disasters have incurred large economic losses in distribution systems. This study proposes a transient simulation and verification method for resilience-enhancement strategies and proposed a ...
Ying Chen, Lu Zhang, Yankan Song, Haixiang Gao   +3 more
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

A user’s guide to coral reef restoration terminologies [PDF]

Global coral reef restoration efforts continue to diversify in approach, location, and socio-ecological context. In parallel, vocabulary has evolved such that practitioners, scientists, policy makers, communicators, and investors must navigate an ...
Goergen, Elizabeth, Goergen, EA, Montoya-Maya, PH, Hein, Margaux Y., Ross, AM, Hoot, Whitney, Fraser, Megan, Suggett, DJ, Hoot, W, Moore, T, Vardi, Tali, Vardi, T, Goergen, Elizabeth A., Ross, Andrew, McLeod, Ian, Ross, Andrew M., Moore, Thomas, McLeod, I, Fraser, M, Suggett, David, Suggett, David J., Hein, MY, Montoya-Maya, Phanor H., Moore, Tom   +23 more
core   +1 more source

Peatland restoration in Norway – evaluation of ongoing monitoring and identification of plant indicators of restoration success

, 2023
<p>Norway launched a national action plan on wetland restoration in 2016. So far, 90% of the restoration effort has been on peatland restoration, with about 140 mires restored so far. There are three main restoration goals stated in the action plan:
Fandrem, Marte, Jokerud, Mari, Lyngstad, Anders, Lunde, Linn Marie, Mehlhoop, Anne Catriona, Kyrkjeeide, Magni Olsen   +5 more
core   +1 more source

Heritage preservation during the Occupation

Bulletin KNOB, 2018
Between 1940 and 1943, during the German Occupation, restoration activities continued unabated in the Netherlands. Existing studies have already shown that, in the context of a reorganization of cultural policy and legislation, the occupier attached ...
Martijn de Jong
doaj   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Policy Language in Restoration Ecology [PDF]

, 2014
Relating restoration ecology to policy is one of the aims of the Society for Ecological Restoration and its journal Restoration Ecology. As an interdisciplinary team of researchers in both ecological science and political science, we have struggled with ...
Sveriges lantbruksuniversitet., Maher Hasselquist, Eliza,, Hof, Anouschka,, Hjältén, Joakim,   +3 more
core   +2 more sources