Results 71 to 80 of about 1,785,585 (297)
Heritage preservation during the Occupation
Bulletin KNOB, 2018 Between 1940 and 1943, during the German Occupation, restoration activities continued unabated in the Netherlands. Existing studies have already shown that, in the context of a reorganization of cultural policy and legislation, the occupier attached ...
Martijn de Jong
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
The Journal of Engineering, 2019 In recent years, major power outages caused by extreme natural disasters have incurred large economic losses in distribution systems. This study proposes a transient simulation and verification method for resilience-enhancement strategies and proposed a ...
Ying Chen +3 more
doaj +1 more source
Public summary of the Santa Monica Bay restoration plan
, 1994 68 pgs.This report combines scientific characterization of the bay described in the Santa Monica Bay Restoration Plan report (1993) and other technical investigations. Recommendations for action which comprise the plan are discussed in full.
Santa Monica Bay Restoration Project
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Lower Passaic River Restoration Project & Newark Bay Study: Public Forums
, 2005 The materials were presented at public forums and were designed to provide information about the Lower Passaic River Restoration Project & Newark Bay Study and project's goals and to discuss sampling work, the dredging pilot study, and the Draft ...
core +1 more source
, 2022 As human activities destroy and degrade the world's ecosystems at unprecedented scales, there is a growing need for evidence-based methods for ecological restoration if we are to preserve biodiversity and ecosystem services.
Yong, Jean W.H, +1 more
core +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Towards an Efficient Self-Healing Strategy for Smart Grids
EnergiesPower system restoration following a large-scale blackout remains a challenging task due to the need to rapidly re-establish service while maintaining operational feasibility.
Abderrazak Khediri +4 more
doaj +1 more source