Results 81 to 90 of about 36,354 (268)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

TOP2 - Partial Parallelization for Paragon

open access: yes, 1992
Parallelization of sequential programs for distributed memory machines generally involves non-local modifications to the program code. Thus, for large applications, it may be very time-consuming even to experiment with different parallelization ...
Detert, Ulrich, Gerndt, Michael
core  

Transparent Parallelization of Binary Code [PDF]

open access: yes, 2011
International audienceThis paper describes a system that applies automatic parallelization techniques to binary code. The system works by raising raw executable code to an intermediate representation that exhibits all memory accesses and relevant ...
Pradelle, Benoit   +2 more
core  

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Invasive Interactive Parallelization

open access: yes, 2006
In this thesis proposal we suggest an interactive method of parallelizing legacy software that is based on separation of concerns and aspect weaving. We statically inject parallelizing code into sequential cores by means of reusable rewrite rules.
Chalabine, Mikhail,
core  

On optimal parallelization of sorting networks

open access: yes, 1990
This paper provides a unifying mathematical proof which replaces a mechanical certification of the optimal parallelization of sorting networks on a case basis. Parallelization of sequential program traces by means of semantic-preserving transformation is
Gannett, Ethan   +2 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Automatic Parallelization of Database Queries

open access: yes, 1990
Although automatic parallelization of conventional language programs is now widely accepted, relatively little emphasis has been placed on automatic parallelization of database query programs (sometimes referred to as “multiple queries” ). In this paper,
Kang, Myong H., Dietz, Henry G.
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

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