Results 41 to 50 of about 492,436 (341)

Snake and spider toxins induce a rapid recovery of function of botulinum neurotoxin paralysed neuromuscular junction [PDF]

, 2015
Botulinum neurotoxins (BoNTs) and some animal neurotoxins (-Bungarotoxin, -Btx, from elapid snakes and -Latrotoxin, -Ltx, from black widow spiders) are pre-synaptic neurotoxins that paralyse motor axon terminals with similar clinical outcomes in patients.
Duregotti, Elisa, Megighian, Aram, Montecucco, Cesare, Pirazzini, Marco, Rigoni, Michela, Scorzeto, M., Zanetti, Giulia   +6 more
core   +2 more sources

Soft Robotic Excretory Care Simulator for Nursing Education: Functional and Perceptual Biomimetics Approach

Advanced Robotics Research, EarlyView.
A soft robotic simulator is developed to replicate the digital removal of feces (DRF), a sensitive yet essential nursing procedure. Integrating soft actuators, sensors, and a realistic rectal model, the simulator balances functional fidelity with perceptual realism. Engineering evaluations and nurse feedback confirm its potential to enhance training in
Shoko Miyagawa, Sota Suzuki, Shizuka Watanabe, Zebing Mao, Young Ah Seong, Toshinori Fujie, Tatsuhiro Horii, Kenjiro Tadakuma, Koichi Suzumori, Hiroyuki Nabae, Shingo Maeda   +10 more
wiley   +1 more source

Monoamine Release in the Cat Lumbar Spinal Cord during Fictive Locomotion Evoked by the Mesencephalic Locomotor Region

Frontiers in Neural Circuits, 2017
Spinal cord neurons active during locomotion are innervated by descending axons that release the monoamines serotonin (5-HT) and norepinephrine (NE) and these neurons express monoaminergic receptor subtypes implicated in the control of locomotion.
Brian R. Noga, Riza P. Turkson, Songtao Xie, Annette Taberner, Alberto Pinzon, Ian D. Hentall   +5 more
doaj   +1 more source

The Role of Dynamic Magnetic Resonance Imaging in Cervical Spondylotic Myelopathy [PDF]

Asian Spine Journal, 2017
Dynamic spinal cord compression has been investigated for several years, but until the advent of open MRI, the use of dynamic MRI (dMRI) did not gain popularity.
John Paul Kolcun, Lee Onn Chieng, Karthik Madhavan, Michael Y. Wang   +3 more
doaj   +1 more source

Terror and bliss? Commonalities and distinctions between sleep paralysis, lucid dreaming, and their associations with waking life experiences [PDF]

, 2016
Sleep paralysis and lucid dreaming are both dissociated experiences related to rapid eye movement (REM) sleep. Anecdotal evidence suggests that episodes of sleep paralysis and lucid dreaming are related but different experiences.
American Academy of Sleep Medicine, Andrade, Angold, Brotherton, Brown, Carlson, Cheyne, Cheyne, Cohen, Denis, Domhoff, Dresler, Espie, Fox, French, Giambra, Giesbrecht, Hartmann, Irwin, Kloet, Koffel, Mahowald, Poerio, Ramsawh, Schredl, Sharpless, Singer, Spielberger, Szklo-Coxe, Takeuchi, Takeuchi, Terzaghi, Tobacyk, Voss, Voss, Watson, Zhiyan   +36 more
core   +2 more sources

A Proof‐of‐Concept Assessment of a Novel Wearable Eyelid Muscle Device: A Pre‐Clinical Animal Cadaver Study for Eyelid Closure Restoration

Advanced Robotics Research, EarlyView.
This article introduces a soft wearable eyelid sling device incorporating a hydraulic soft artificial muscle (SAM) for achieving complete closure of an eyelid. The SAM is driven by a cam mechanism that provides a displacement profile closely matched with those of a healthy eyelid.
Patrick Pruscino, Phuoc Thien Phan, James Davies, Bibhu Sharma, Tianruo Guo, Chi Cong Nguyen, Nigel H. Lovell, Thanh Nho Do   +7 more
wiley   +1 more source

Single cell RNA sequencing after moderate traumatic brain injury: effects of therapeutic hypothermia

Journal of Neuroinflammation
Traumatic brain injury (TBI) initiates a cascade of cellular and molecular events that promote acute and long-term patterns of neuronal, glial, vascular, and synaptic vulnerability leading to lasting neurological deficits. These complex responses lead to
Nadine A. Kerr, James Choi, Simone Y. Mohite, Praveen Kumar Singh, Helen M. Bramlett, Jae K. Lee, W. Dalton Dietrich   +6 more
doaj   +1 more source

Fibrotic scar after experimental autoimmune encephalomyelitis inhibits oligodendrocyte differentiation

Neurobiology of Disease, 2020
Remyelination failure is a crucial component of disease progression in the autoimmune demyelinating disease Multiple Sclerosis (MS). The regenerative capacity of oligodendrocyte progenitor cells (OPCs) to replace myelinating oligodendrocytes is likely ...
Stephanie L. Yahn, Jiajun Li, Irene Goo, Han Gao, Roberta Brambilla, Jae K. Lee   +5 more
doaj   +1 more source

Cromakalim (BRL 34915) restores in vitro the membrane potential of depolarized human skeletal muscle fibres [PDF]

, 1989
The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as K+ channel openers, on the electrical activity of human skeletal muscle.
Grafe, Peter, Lehmann-Horn, Frank, Spuler, A.   +2 more
core   +1 more source

Multi‐Material Additive Manufacturing of Soft Robotic Systems: A Comprehensive Review

Advanced Robotics Research, EarlyView.
This review explores the transformative role of multi‐material additive manufacturing (MMAM) in the development of soft robotic systems. It presents current techniques, materials, and design strategies that enable functionally graded and adaptive structures.
Ritik Raj, Quan‐Chen Song, Jia‐Yang Juang   +2 more
wiley   +1 more source