Results 71 to 80 of about 7,189,567 (273)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Recursive Parameter Estimation: Convergence

open access: yes, 2007
We consider estimation procedures which are recursive in the sense that each successive estimator is obtained from the previous one by a simple adjustment.
Sharia, Teo
core   +2 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Accurate calibration of stereo cameras for machine vision

open access: yesJournal of Computer Science and Technology, 2004
Camera calibration is an important task for machine vision, whose goal is to obtain the internal and external parameters of each camera. With these parameters, the 3D positions of a scene point, which is identified and matched in two stereo images, can ...
Liangfu Li, Zuren Feng, Yuanjing Feng
doaj  

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

GRB spectral parameter modeling

open access: yes, 2010
Fireball model of the gamma-ray bursts (GRBs) predicts generation of numerous internal shocks, which efficiently accelerate charged particles and generate relatively small-scale stochastic magnetic and electric fields.
Fleishman, Gregory D., Urtiev, Fedor A.
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

A parameter-free hedging algorithm [PDF]

open access: yes, 2009
We study the problem of decision-theoretic online learning (DTOL). Motivated by practical applications, we focus on DTOL when the number of actions is very large.
Chaudhuri, Kamalika   +2 more
core   +3 more sources

Gr\"uneisen Parameter for Gases

open access: yes, 2016
The Gr\"uneisen ratio ($\Gamma$), i.e.\,the ratio of the linear thermal expansivity to the specific heat at constant pressure, quantifies the degree of anharmonicity of the potential governing the physical properties of a system.
de Souza, Mariano   +4 more
core   +1 more source

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