Results 101 to 110 of about 764,789 (277)
On Regularization Parameter Estimation under Covariate Shift
, 2016 This paper identifies a problem with the usual procedure for L2-regularization parameter estimation in a domain adaptation setting. In such a setting, there are differences between the distributions generating the training data (source domain) and the ...
Kouw, Wouter M., Loog, Marco
core +1 more source
Adaptive Semiparametric Estimation of the Memory Parameter
Journal of Multivariate Analysis, 2000 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Liudas Giraitis +2 more
openaire +3 more sources
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Fuzzy dynamic parameter adaptation in the bird swarm algorithm for neural network optimization. [PDF]
Soft comput, 2022 Melin P +3 more
europepmc +1 more source
Synchronization and Control of Spatiotemporal Chaos using Time-Series Data from Local Regions
, 1997 In this paper we show that the analysis of the dynamics in localized regions, i.e., sub-systems can be used to characterize the chaotic dynamics and the synchronization ability of the spatiotemporal systems.
Kulkarni, B. D. +2 more
core +2 more sources
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Lottery Rank-Pruning Adaptation Parameter Efficient Fine-Tuning
MathematicsRecent studies on parameter-efficient fine-tuning (PEFT) have introduced effective and efficient methods for fine-tuning large language models (LLMs) on downstream tasks using fewer parameters than required by full fine-tuning.
Juhyeong Kim, Gyunyeop Kim, Sangwoo Kang
doaj +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Activation-Guided Low-Rank Parameter Adaptation for Efficient Model Fine-Tuning
IEEE AccessFine-tuning large language models is computationally expensive, and while existing parameter-efficient methods like Low-Rank Adaptation (LoRA) reduce computational costs, they are limited by suboptimal initialization strategies.
Qingchen Wang, Shengyu Shen
doaj +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source