Results 101 to 110 of about 2,795,142 (309)
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
A Parameter Adaptation Strategy for the Parallel Capacity Expansion of VSGs in New Energy Units
EnergiesAgainst the engineering background of continuous expansion of renewable energy units, in islanded microgrids employing virtual synchronous generator (VSG) control, newly connected VSGs often cannot obtain the key control parameters of existing VSGs ...
Penghui Liu, Xihang Zhou
doaj +1 more source
Nonlocal Means Image Denoising With Minimum MSE-Based Decay Parameter Adaptation
IEEE Access, 2019 Nonlocal means (NLM), a patch-based nonlocal recovery paradigm, has attracted much attention in recent decades. The decay parameter will greatly affect restoration performance of the NLM method.
Yi Zhan +3 more
doaj +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Joining the dots: hydrology, freshwater ecosystem values and adaptation options [PDF]
, 2013 The objective of this research was to investigate and test the necessary steps in developing an adaptation planning framework for freshwater biodiversity.
Leon Barmuta, Peter Davies, Anne Watson
core
Lottery Rank-Pruning Adaptation Parameter Efficient Fine-Tuning
MathematicsRecent studies on parameter-efficient fine-tuning (PEFT) have introduced effective and efficient methods for fine-tuning large language models (LLMs) on downstream tasks using fewer parameters than required by full fine-tuning.
Juhyeong Kim, Gyunyeop Kim, Sangwoo Kang
doaj +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Decision-making for climate change adaptation: A systems thinking approach [PDF]
, 2013 The impacts of climate change are exacerbated by inefficient adaptation and mitigation decision making, due to the complexity of the decision-making environment. As a consequence, there is no single approach to planning and decision making.
Kambiz Maani, Maani, Kambiz
core
Engineering ProceedingsAspect-based sentiment analysis (ABSA) plays a vital role in deriving fine-grained sentiment from textual content. As large language models (LLMs) are increasingly adopted for automated data annotation in natural language processing (NLP), concerns have ...
Pei Ying Lim, Chuk Fong Ho, Chi Wee Tan
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source