Results 81 to 90 of about 524,430 (317)

Using Covariance Factor in Genetic Parameter Estimation

open access: yesVeterinary Sciences and Practices, 2022
Ömer ELTAS, Mehmet TOPAL
doaj   +1 more source

On parameter estimation for locally stationary long-memory processes [PDF]

open access: yes
We consider parameter estimation for time-dependent locally stationary long-memory processes. The asymptotic distribution of an estimator based on the local infinite autoregressive representation is derived, and asymptotic formulas for the mean squared ...
Jan Beran
core  

Structured parameter estimation for LFG-DOP using Backoff [PDF]

open access: yes, 2003
Despite its state-of-the-art performance, the Data Oriented Parsing (DOP) model has been shown to suffer from biased parameter estimation, and the good performance seems more the result of ad hoc adjustments than correct probabilistic generalization ...
Hearne, Mary   +2 more
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

A Parameter Estimation Method for Nonlinear Systems Based on Improved Boundary Chicken Swarm Optimization

open access: yesDiscrete Dynamics in Nature and Society, 2016
Parameter estimation is an important problem in nonlinear system modeling and control. Through constructing an appropriate fitness function, parameter estimation of system could be converted to a multidimensional parameter optimization problem.
Shaolong Chen   +9 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Intelligent joint channel parameter estimation techniques for mobile wireless positioning applications [PDF]

open access: yes, 2010
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Mobile wireless positioning has recently received great attention. For mobile wireless communication networks, an inherently suitable approach is to obtain
Li, Wei
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Statistics with estimated parameters

open access: yes, 2007
Summary: This paper studies a general problem of making inferences for functions of two sets of parameters where, when the first set is given, there exists a statistic with a known distribution. We study the distribution of this statistic when the first set of parameters is unknown and is replaced by an estimator. We show that under mild conditions the
YANG, Zhenlin   +2 more
openaire   +1 more source

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