Results 71 to 80 of about 524,430 (317)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
A comparison of parameter estimation algorithms for estimating a polytomous log-linear cognitive diagnosis model for polytomous attributes [PDF]
, 2019 Parameter estimation techniques such as an expectation-maximization (EM) algorithm have been used ubiquitously to estimate cognitive diagnosis models (CDM).
Strachan, Tyler Jeffrey +1 more
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Parameter Estimation of Exciation Systems
, 2009 LAI, JUMING. Parameter Estimation of Excitation Systems. (Under the direction of Mesut E. Baran) The purpose of the research has been to develop a methodology to simplify the process of parameter estimation of excitation systems. There are two parts in
Lai, Juming
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Parameter Estimation and Statistical Test on Zero Inflated Poisson Inverse Gaussian Regression (ZIPIGR) Model with Exposure Variable [PDF]
, 2023 The over dispersion case is one of the assumptions that violated in the data count model using Poisson regression, which was caused by the presence of many zero values (more than 30%) on the response variable.
Purhadi, Purhadi +2 more
core
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
A Global Approach to Parameter Estimation of Chaotic Dynamical Systems
, 1992 We present a novel approach to parameter estimation of systems with complicated dynamics, as well as evidence for the existence of a universal power law that enables us to quantify the dependence of global geometry on small changes in the ...
Siapas, Athanassios G.
core
Parameter estimation for peaky altimetric waveforms [PDF]
, 2013 Much attention has been recently devoted to the analysis of coastal altimetric waveforms. When approaching the coast, altimetric waveforms are sometimes corrupted by peaks caused by high reflective areas inside the illuminated land surfaces or by the ...
Boy, François +6 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source