Results 71 to 80 of about 393,308 (312)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Traffic congestion parameter estimation in time series of airborne optical remote sensing images [PDF]

open access: yes, 2009
In this paper we propose a new model based traffic parameter estimation approach in congested situations in time series of airborne optical remote sensing data.
Palubinskas, Gintautas   +2 more
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Text Extraction from Web Images Based on Human Perception and Fuzzy Inference [PDF]

open access: yes, 2001
There is a significant need to extract and recognise the semantically-important text contained in images on Web pages. This paper proposes a new approach to text extraction from this special class of images.
A. Antonacopoulos   +3 more
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Parameter extraction of superconducting integrated circuits [PDF]

open access: yes, 2006
Thesis (MScEng (Electrical and Electronic Engineering))--University of Stellenbosch, 2006.Integrated circuits are expensive to manufacture and it is important to verify the correct operation of a circuit before fabrication.
Lotter, Pierre
core  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

PARAMETERS OF FUEL JET EXTRACTION IN VIDEO

open access: yesTRANSPORT, 2005
The statistical rating of the image of a fuel jet allows to allocate the zones with homogeneous brightness, to define the distribution of masses and the concentration in a fuel jet and to look after their dynamics. In the research the coding with the usage of Byeses's definition of the aposteriory probability of the presence of the given brightness in ...
Eskov, Alexsander   +2 more
openaire   +4 more sources

Static Characterization and parameter Extraction in MOS Transistors [PDF]

open access: yes, 1998
This paper describes the basic concepts for efficient parameter extraction. The focus is on efficiency in parameter extraction and often analytical manipulation of the model equations can be used to increase efficiency.
Jeppson, Kjell,   +2 more
core   +1 more source

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