Results 111 to 120 of about 560,784 (316)
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Connecting identification and robust control: a new challenge [PDF]
, 1992 Until recently identification theory had not focused upon delivering accurate uncertainty bounds around the estimated model. In addition, in adaptive control design, not much effort has been devoted to the effect of the controller on the quality of the ...
Gevers, Michel +1 more
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Identification of Dynamical Models of Spatio-temporal Pattern Formation with Applications to Slime Mould [PDF]
, 2011 Spatio-temporal systems are non-linear dynamical systems which include both time and space information. Many natural phenomena and processes can be described by spatio-temporal models, such as pattern formation, chemical reactions and physical dynamics ...
Wang, Shu
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Parallelized Genetic Identification of the Thermal-Electrochemical Model for Lithium-Ion Battery
Advances in Mechanical Engineering, 2013 The parameters of a well predicted model can be used as health characteristics for Lithium-ion battery. This article reports a parallelized parameter identification of the thermal-electrochemical model, which significantly reduces the time consumption of
Liqiang Zhang +5 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Aspects of self-adaptive control using parameter perturbation techniques [PDF]
This thesis is concerned with the performance of a method of simultaneous identification and optimization of a control system, employing a parameter perturbation technique.
Pawley, Anthony John Robert
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
The design of periodic excitations for dynamic system identification [PDF]
System identification techniques are developed for modelling linear and nonlinear systems. The main results of the work are concerned with the design and utilisation of periodic perturbation signals in general areas of time- and frequency-domain ...
McCormack, Anthony Sean
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EnergiesWith the increasing penetration of renewable energy generation, analysis of the transient characteristics of doubly fed induction generators, as the mainstream wind turbine configuration, is made highly significant both theoretically and practically ...
Jun Deng +6 more
doaj +1 more source