Results 41 to 50 of about 1,479,521 (268)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Ensemble Kalman filter for neural network based one-shot inversion
, 2020 We study the use of novel techniques arising in machine learning for inverse problems. Our approach replaces the complex forward model by a neural network, which is trained simultaneously in a one-shot sense when estimating the unknown parameters from ...
Guth, Philipp A. +2 more
core +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Adaptive LADRC Parameter Optimization in Magnetic Levitation
IEEE Access, 2021 In this study, an adaptive linear active disturbance rejection control is proposed to achieve steady levitation of the magnetic levitation ball. The proposed algorithm was designed and its convergence was proven via derivation.
Qinghua Ouyang +3 more
doaj +1 more source
An RRAM Biasing Parameter Optimizer [PDF]
IEEE Transactions on Electron Devices, 2015 Research on memory devices is a highly active field, and many new technologies are being constantly developed. However, characterizing them and understanding how to bias for optimal performance are becoming an increasingly tight bottleneck. Here, we propose a novel technique for extracting biasing parameters, conducive to desirable switching behavior ...
Serb, Alexantrou +2 more
openaire +3 more sources
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Parameter Inference in the Pulmonary Circulation of Mice [PDF]
, 2017 This study focuses on parameter inference in a pulmonary blood cir- culation model for mice. It utilises a fluid dynamics network model that takes selected parameter values and aims to mimic features of the pulmonary haemody- namics under normal ...
Colebank, Mitchel +6 more
core
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Driver’s Workspace Parameter Optimization
Механика машин, механизмов и материалов, 2011 In the article the issue concerning driver’s workspaces of existing vehicles and vehicles to be designed is being researched in order to increase the efficiently of human resources.
T.V. Kipen +3 more
doaj
Jurnal Ilmu Komputer dan Informasi, 2017 SVM (Support Vector Machine) with RBF (Radial Basis Function) kernel is a frequently used classification method because usually it provides an accurate results.
Rarasmaya Indraswari, Agus Zainal Arifin
doaj +1 more source