Results 61 to 70 of about 1,479,521 (268)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Seismic Model Parameter Optimization for Building Structures

Sensors, 2020
Structural dynamic modeling is a key element in the analysis of building behavior for different environmental factors. Having this in mind, the authors propose a simple nonlinear model for studying the behavior of buildings in the case of earthquakes ...
Lengyel Károly, Ovidiu Stan, Liviu Miclea   +2 more
doaj   +1 more source

Throughput-Oriented Full-Duplex Cognitive Radio Network Parameter Optimization

International Journal of Antennas and Propagation, 2022
Full-duplex cooperative spectrum sensing (FD-CSS) is an important research field in the field of spectrum sensing. In the FD-CSS network, the secondary user (SU) senses the usage status of the authorized spectrum by the primary user (PU) through the ...
Haibin Jiang, Zhiyong Yu, Jian Yang, Kai Kang   +3 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Parameter optimization for the unimon qubit

Physical Review Research
Inductively shunted superconducting qubits, such as the unimon qubit, combine high anharmonicity with protection from low-frequency charge noise, positioning them as promising candidates for the implementation of fault-tolerant superconducting quantum ...
Rostislav Duda, Eric Hyyppä, Olli Mukkula, Vasilii Vadimov, Mikko Möttönen   +4 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Research Prospects for the Optimization of Magneto-Optical Trap Parameters for Cold Atom Interferometers

Applied Sciences
This study examines parameter optimization for magneto-optical traps (MOTs) to increase trapping efficiency and improve cold atom interferometer performance.
Dongyi Li, Fangjun Qin, Rui Xu, An Li
doaj   +1 more source

A Parameter Estimation Method for Nonlinear Systems Based on Improved Boundary Chicken Swarm Optimization

Discrete Dynamics in Nature and Society, 2016
Parameter estimation is an important problem in nonlinear system modeling and control. Through constructing an appropriate fitness function, parameter estimation of system could be converted to a multidimensional parameter optimization problem.
Shaolong Chen, Renyu Yang, Renhuan Yang, Liu Yang, Xiuzeng Yang, Chuangbiao Xu, Baoguo Xu, Huatao Zhang, Yaosheng Lu, Weiping Liu   +9 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source