Results 91 to 100 of about 3,493,044 (354)

Exploring parameter spaces in complex dynamics

Selecciones Matemáticas, 2023
We show the structure of the parameter space for a family of rational maps containing Blaschke products. Through numerical simulations using the orbit of a single critical point, we reveal the existence of infinitely many Mandelbrot-like sets along the ...
Pedro Iván Suárez Navarro
doaj   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Energy conditions in mimetic-$f(R)$ gravity

, 2017
The energy conditions of mimetic-$f(R)$ gravity theory is analyzed. We will obtain the parameter space of the theory in some special forms of $f(R)$ in which the self-acceleration is allowed.
Haghani, Zahra, Shahidi, Shahab, Shiravand, Maryam   +2 more
core   +1 more source

A converse landing theorem in parameter spaces [PDF]

Journal of Mathematical Analysis and Applications, 2022
In this article, we prove that for several one-dimensional holomorphic families of holomorphic maps, in the parameter plane, there exists a local piece of a curve that lands at a given parabolic parameter, in the spirit of well-known results about the quadratic and the exponential families. We also show that, under some assumptions, this general result
openaire   +3 more sources

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

Molecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas, Konstantinos Voutetakis, Vivian Kosmidou, Spyridon Tsikalakis, Spyridon Roditis, Konstantinos Pateas, Ryangguk Kim, Kymberleigh Pagel, Stephan Wolf, Gregor Warsow, Antonia Dimitrakopoulou‐Strauss, Georgios N. Zografos, Alexander Pintzas, Johannes Betge, Olga Papadodima, Stefan Wiemann   +15 more
wiley   +1 more source

Solar and atmospheric neutrino oscillations with three flavours

, 1995
We analyze the solar and the atmospheric neutrino problems in the context of three flavour neutrino oscillations. We assume a mass hierarchy in the vacuum mass eigenvalues $\mu_3^2 \gg \mu_2^2 \geq \mu_1^2$, but make no approximation regarding the ...
A. Acker, A. K. Mann, A. S. Joshipura, A. S. Joshipura, C. Giunti, Ch. Berger, D. Casper, D. Harley, G. L. Fogli, G. Rajasekaran, H. A. Bethe, J. Bahcall, J. N. Bahcall, J. N. Bahcall, K. S. Hirata, K. V. L. Sarma, L. Wolfenstein, L. Wolfenstein, M. Aglietta, M. Nakahata, M. V. N. Murthy, Mohan Narayan, N. Hata, N. Hata, P. Anselman, R. Becker Szendy, S. M. Bilenky, S. P. Mikheyev, S. Uma Sankar, Stephen Parke, T. K. Kuo, T. K. Kuo, W. Kwong, Y. Fukuda   +33 more
core   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Ratchet transport and periodic structures in parameter space

, 2011
Ratchet models are prominent candidates to describe the transport phenomenum in nature in the absence of external bias. This work analyzes the parameter space of a discrete ratchet model and gives direct connections between chaotic domains and a family ...
Albuquerque, Holokx A., Beims, Marcus W., Celestino, Alan, Manchein, Cesar   +3 more
core   +1 more source

Parameter spaces of massive IIA solutions [PDF]

Journal of High Energy Physics, 2011
We find a new class of N=2 massive IIA solutions whose internal spaces are S^2 fibrations over S^2 x S^2. These solutions appear naturally as massive deformations of the type IIA reduction of Sasaki-Einstein manifolds in M-theory, including Q^{1,1,1} and Y^{p,k}, and play a role in the AdS4/CFT3 correspondence.
TOMASIELLO, ALESSANDRO, ZAFFARONI, ALBERTO   +1 more
openaire   +3 more sources

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source