Results 91 to 100 of about 5,756,257 (288)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Submersible Space Training Suit Preliminary Test Results and Review

Immediate accessThis item is made available by the University of Arizona Center for Human Space Exploration (CHaSE) with support from the University of Arizona Libraries.
Smith, Cameron, Tresch, Trent
core   +4 more sources

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Scalar phenomenology in type-II seesaw model

Journal of High Energy Physics, 2019
In this work we study the viable parameter space of the scalar sector in the type-II seesaw model. In identifying the allowed parameter space, we employ constraints from low energy precision measurements, theoretical considerations and the 125-GeV Higgs ...
R. Primulando, J. Julio, P. Uttayarat
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Tracking discontinuities in parameter space

Journal of High Energy Physics
We develop a geometric framework in Feynman-parameter space to determine constraints on the sequential discontinuities of Feynman integrals. Our method is based on tracking the deformation of the integration contour as external kinematics are ...
Ruth Britto, Holmfridur S. Hannesdottir
doaj   +1 more source

Rescuing leptogenesis parameter space of inverse seesaw

Physics Letters B
In a pure inverse seesaw framework, achieving a substantial lepton asymmetry that can be converted into the observed baryon asymmetry of the Universe is extremely challenging.
Ananya Mukherjee, Abhijit Kumar Saha
doaj   +1 more source

Parameter-space topology of models for cell polarity

New Journal of Physics, 2014
Reaction–diffusion systems have been widely successful in the theoretical description of biological patterning phenomena, giving rise to numerous models based on differing mechanisms, mathematical implementations and parameter choices.
Philipp Khuc Trong, Ernesto M Nicola, Nathan W Goehring, K Vijay Kumar, Stephan W Grill   +4 more
doaj   +1 more source

Bifurcation currents and equidistribution in parameter space [PDF]

, 2014
This chapter reviews the use of techniques of positive currents for the study of parameter spaces of one-dimensional holomorphic dynamical systems (rational mappings on P¹ or subgroups of the Möbius group PSL(2,C)). The topics covered include the construction of bifurcation currents and the characterization of their supports, the equidistribution ...
openaire   +3 more sources