Results 31 to 40 of about 1,981,405 (253)
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
This study aims to accurately forecast monthly native chicken egg production using the Seasonal Autoregressive Integrated Moving Average (SARIMA) model with parameter optimization.
Rendra Gustriansyah +3 more
doaj +1 more source
Parameter values after tuning.
Parameter values after tuning.
Hashem Tamimi (3359189) +2 more
core +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
PVP: Pre-trained Visual Parameter-Efficient Tuning [PDF]
Large-scale pre-trained transformers have demonstrated remarkable success in various computer vision tasks. However, it is still highly challenging to fully fine-tune these models for downstream tasks due to their high computational and storage costs ...
Hu, Qingyong +5 more
core +1 more source
ObjectiveThe development of primary logistics plans for refined oil currently relies heavily on logistics management software based on optimization models.
Guangtao FU +7 more
doaj +1 more source
Calibration of tuning parameter for SWAM using empirical data.
We calibrated our tuning parameter using GEUVADIS data as our external validation. As a result, we set the default value of this tuning parameter to 3 in our software, which we believe performs best.
Hyun Min Kang (9690325) +1 more
core +1 more source
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source

