Results 51 to 60 of about 701,150 (283)

The Higgs boson mass in a natural MSSM with nonuniversal gaugino masses at the GUT scale

open access: yes, 2012
We identify a parameter region where the mass of the lightest CP-even Higgs boson resides in $124.4-126.8$ GeV, and at the same time the degree of tuning a Higgsino-mass parameter (so-called $\mu$-parameter) is relaxed above 10% in the minimal ...
Aad   +41 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Experiential History as a Tuning Parameter for Attention

open access: yesJournal of Cognition, 2018
[Peer commentary on “Visual selection: usually fast and automatic; seldom slow and volitional,” by J. Theeuwes]. 'Journal of Cognition'. In his current opinion piece, Theeuwes emphasizes the role of selection history as a third source of attentional ...
J. H. Kryklywy, R. M. Todd
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Artificial Bee Colony Algorithm Improved with Evolutionary Operators

open access: yesJournal of Computer Science and Technology, 2018
In this paper, we design, implement, and analysis the replacement of the method to create new solutions in artificial bee colony algorithm by recombination operators, since the original method is similar to the recombination process used in evolutionary ...
Gabriela Minetti, Carolina Salto
doaj   +1 more source

Radiatively Generated Maximal Mixing Scenario for the Higgs Mass and the Least Fine Tuned Minimal Supersymmetric Standard Model

open access: yes, 2006
We argue that given the experimental constraints on the Higgs mass the least fine tuned parameter space of minimal supersymmetric standard model is with negative stop masses squared at the grand unification scale.
Dermisek, Radovan, Kim, Hyung Do
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Neural Network-Based Parameter Tuning for Multi-Armed Bandit Algorithms [PDF]

open access: yesITM Web of Conferences
This paper presents a novel approach for dynamically tuning the exploration parameter in Multi-Armed Bandit (MAB) algorithms using Deep Q-Networks (DQN), focusing on enhancing performance in static and dynamic environments.
Shi Yuhan
doaj   +1 more source

TIGER: A Tuning-Insensitive Approach for Optimally Estimating Gaussian Graphical Models [PDF]

open access: yes, 2012
We propose a new procedure for estimating high dimensional Gaussian graphical models. Our approach is asymptotically tuning-free and non-asymptotically tuning-insensitive: it requires very few efforts to choose the tuning parameter in finite sample ...
Liu, Han, Wang, Lie
core  

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