Results 161 to 170 of about 6,062,625 (214)

Capture of long‐missing heme oxygenases that degrade both heme b and heme c

mLife, EarlyView.
Abstract Heme serves as a crucial cofactor for hemoproteins and as an iron reservoir; yet, its accumulation is toxic, necessitating efficient degradation pathways. While the catabolism of free heme b is well characterized, the enzymes that disrupt its counterpart covalently tethered to a peptide (heme c) have remained elusive.
Jiyuan Hou, Wenhan Dong, Hui Yang, Yuxuan Liang, Haichun Gao   +4 more
wiley   +1 more source

One-step enzymatic synthesis of medium molecular weight dextran using engineered dextransucrase DarM from <i>Leuconostoc citreum</i> CBA3623. [PDF]

Front Microbiol
Zhang W, Wang X, Liu J, Huang S, Yang L, Li J, Wei M, Qin Z, Yang D, Pan L.   +9 more
europepmc   +1 more source

The b‐Value Dependence for Higher‐Degree Spherical Harmonic Powers of the Diffusion MRI Signal Follows Stick Model Predictions in White Matter

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To compare the dependence on b‐value of the spherical harmonic powers for the diffusion MRI signal in white matter to theoretical predictions from the stick model of water diffusion within axons. Methods Diffusion MRI data were acquired at 3 T in three healthy adults with 10 b‐value shells (b = 1000–10 000 s/mm2) and 64 directions per ...
Hunter G. Moss, Jens H. Jensen, Andreana Benitez   +2 more
wiley   +1 more source

Efficient Synthesis of Glucovanillin and Elucidation of Its Molecular Mechanisms in Ameliorating T2DM via Core Target Modulation and α-Glucosidase Inhibition. [PDF]

Molecules
Zhang H, Zhang W, Li F, Lu X, Yan Y, Zhang D.   +5 more
europepmc   +1 more source

An Approach for Computationally Efficient Yet Accurate Modeling of Vibrating Machines With Neidhart Springs

International Journal of Mechanical System Dynamics, EarlyView.
ABSTRACT Accurate modeling of vibrating machines equipped with Neidhart springs is challenging due to the strong nonlinearities introduced by the elastomer–metal torsional elements and the constraints imposed by their kinematic arrangement. Multibody modeling methodologies for such vibrating machines are often computationally demanding, thus limiting ...
Davide Galli, Veit Gufler, Andrea Giusti, Renato Vidoni   +3 more
wiley   +1 more source

Development of an Agent-Based Model to Investigate Durability of Factor IX Activity in Hemophilia B Patients Treated With Etranacogene Dezaparvovec. [PDF]

CPT Pharmacometrics Syst Pharmacol
Li Y, Nandy P, Jordie E, Knab T, Peppel K, Kirouac DC, Wilkins AK, Nuthalapati S.   +7 more
europepmc   +1 more source

Monitoring shallow geothermal aquifers with active‐source distributed acoustic sensing: A prognostic feasibility study on the University of Leeds Geothermal Campus

Near Surface Geophysics, EarlyView.
Abstract The United Kingdom's shallow aquifers offer significant but underdeveloped geothermal energy resource. Seismic methods can help address this by improving the understanding of aquifer heterogeneity and potentially allowing long‐term monitoring of thermal plumes.
Adam D. Booth, Roger A. Clark, Andy Nowacki, Ravi Myanger, Joseph Kelly, Sjoerd de Ridder, Arka Dyuti Sarkar, Fleur Loveridge, Richard Collier, Emma Bramham, David Healy   +10 more
wiley   +1 more source

Coalition of explainable artificial intelligence and quantum computing in precision medicine. [PDF]

Comput Struct Biotechnol J
Ray S, Bhattacharya P, Mattar EA, Mukhopadhyay A.   +3 more
europepmc   +1 more source

Recycling of Thermoplastic Unidirectional Tapes: An Image‐Analysis Method for Measuring Residual Glass‐Fiber Length in Convoluted Fiber Clusters

Polymer Composites, EarlyView.
Development of a rapid, low‐cost method for measuring residual glass fibre length: samples are collected by tweezers, prepared via submersion, imaged with a flatbed scanner as a cost‐effective alternative to microscopy, and analyzed for fibre length independently of image acquisition.
Tina Mayrhofer, Bernhard Cäsar, Klaus Straka, Gerald Roman Berger‐Weber   +3 more
wiley   +1 more source