Results 191 to 200 of about 225,085 (221)

Near-cognate tRNAs dominate codon decoding times in simulated ribosomes. [PDF]

Nucleic Acids Res
Hedayioglu F, Hargreaves EJ, Kurusamy S, Thaventhiran JED, Willis AE, Smales CM, von der Haar T.   +6 more
europepmc   +1 more source

Mitochondrial Ca2+ overload is a pivotal risk factor for lethal ventricular arrhythmias due to the oxidation of mitochondrial respirasome and energetic failure

British Journal of Pharmacology, EarlyView.
The data that support the findings of this study are available from the corresponding author upon reasonable request. Some data may not be made available because of privacy or ethical restrictions. Background and Purpose Ventricular arrhythmias are a leading cause of death among patients with cardiovascular diseases and are associated with elevated ...
Felipe de Jesús Salazar‐Ramírez, Luis Alberto Luévano‐Martínez, Abraham Méndez‐Fernández, Judith Bernal‐Ramírez, Carolina A. Morales‐Ochoa, Christian Silva‐Platas, Alfredo Cabrera‐Orefice, Ana C. Murrieta, José Luis Velasco‐Bolom, Gricelda Mendiola‐Garza, Flavio Contreras‐Torres, Guillermo Torre‐Amione, Ernesto A. Aiello, Gerardo García‐Rivas   +13 more
wiley   +1 more source

Identification of 2,3-oxidosqualene cyclase gene in <i>Eleutherococcus senticosus</i> and its regulatory mechanism in saponin synthesis. [PDF]

Hortic Res
Cui Y, Ma J, Jiao M, Zhao X, Ding J, Feng C, Liu P, Long Y, Xing Z.   +8 more
europepmc   +1 more source

Matsupexole: A novel nonergot dopamine receptor agonist with sustained efficacy in a rat model of Parkinson's disease and limited off‐target activity

British Journal of Pharmacology, EarlyView.
Background and Purpose Dopamine receptor agonists, particularly targeting the dopamine D2L receptor (D2LR), have been used to treat Parkinson's disease (PD). However, valvular heart disease and somnolence, mainly caused by activating the serotonin 5‐HT2B receptor (5‐HT2BR) and dopamine D3 receptor (D3R), respectively, currently challenge their clinical
Takayuki Suzuki, Fumiki Oana, Masaki Oota, Yuma Handa, Osamu Kaminuma   +4 more
wiley   +1 more source

Akkermansia muciniphila alleviates metabolic disorders through gut microbiota-mediated tryptophan regulation. [PDF]

AMB Express
Zhang F, Tian J, Li JT, Zhang T, Wang X.
europepmc   +1 more source

Bioinformatics Approach to mTOR Signaling Pathway-Associated Genes and Cancer Etiopathogenesis. [PDF]

Genes (Basel)
Ozdilli K, Oztan G, Kıvanç D, Oğuz R, Oguz F, Ciftci HS.   +5 more
europepmc   +1 more source

Bioinformatic Evidence Suggesting a Dopaminergic-Related Molecular Association Between GenX Exposure and Major Depressive Disorder. [PDF]

Toxics
Huang X, Wang Y, Zheng Y, Wang W, Lu Y.
europepmc   +1 more source

Development of an in vitro multi-enzyme system for efficient one-pot biosynthesis of sorbitol from fructose-6-phosphate. [PDF]

Bioresour Bioprocess
Shen K, Zhu CN, Xu JH, Zheng GW, Chen Q.
europepmc   +1 more source

Development of several machine learning based models for determination of small molecule pharmaceutical solubility in binary solvents at different temperatures. [PDF]

Sci Rep
Alqarni M, Alqarni A.
europepmc   +1 more source

Dihydroartemisinin Promotes N1 Polarization of Tumor-Associated Neutrophils and Enhances Their Anti-Tumor Activity via Hub Gene Modulation. [PDF]

Pharmaceuticals (Basel)
Guo W, Liu Y, Ma W, Wang J, Chen B, Fan L.   +5 more
europepmc   +1 more source