Results 101 to 110 of about 5,040,431 (241)
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Parameter Sensitivity in LSMs: An Analysis Using Stochastic Soil Moisture Models and ELDAS Soil Parameters [PDF]
, 2009 Integration of simulated and observed states through data assimilation as well as model evaluation requires a realistic representation of soil moisture in land surface models (LSMs).
Hurk, B., van den +3 more
core +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
AN ADEQUATE POTENTIAL BASED ON MOLECULAR INFORMATION: SELECTION AND APPROBATION [PDF]
Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2013 The results are given obtained due to a new approach to description of the potential curves shapes, defined links of the special point coordinates for the curves with the critical parameters and the analytical and calculation possibilities of the ...
G.G. Petrik
doaj
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
CoRR, 2015 In resolving instances of a computational problem, if multiple instances of interest share a feature in common, it may be fruitful to compile this feature into a format that allows for more efficient resolution, even if the compilation is relatively expensive.
openaire +4 more sources
The Effect of Process Parameters on the Mechanical and Optical Properties of Cast Film [PDF]
, 2005 This project will examine the effect of process parameters on the properties of a semi-crystalline cast film. The objective was to conduct the experiment on a commercial scale extruder.
West, Solomon
core
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
An interview on linguistic variation with Noam Chomsky
Isogloss, 2015 This is an interview to Noam Chomsky (MIT) on linguistic variation.
Noam Chomsky
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source