Results 81 to 90 of about 5,040,431 (241)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Determination of Parameters for Assessing Bus Transit and Service Area Relationships along EDSA [PDF]
, 2010 Through the use of boarding and alighting data from a thoroughfare spanning across a metropolis, it can be possible to derive associations between transit activity and area characteristics. This study aims to determine statistical relationships
Regidor, Jose Regin F. +2 more
core
Soil parameters affecting longleaf pine (Pinus palustris) site quality in east Texas
Forestry ResearchThe decline since European colonization in longleaf pine (Pinus palustris Mill.) within its range in the southeastern United States, attributed to factors including both site conversion and fire exclusion has spurred interest in the re-establishment of ...
Brian P. Oswald +2 more
doaj +1 more source
Comparative Economic Research, 2018 The preliminary results of the development of the initial theoretical, methodological and applied methodological provisions for the study of the profile of a modern Ukrainian manager are presented in the context of predicting its transformation in the ...
Beata Glinkowska +1 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
SOME STATISTICAL DISTRIBUTIONS, WHICH DESCRIBE THE NANOTOPOGRAPHY OF TECHNICAL SURFACES
Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2020 The nanotopography of engineering surfaces of machine parts made of high alloy heat-treated steel and electric silver after finishing mechanical treatment was studied.
V.V. Izmailov, M.V. Novoselova
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Stochastic Generator of a New Family of Lifetime Distributions with Illustration
Revstat Statistical JournalIn this article, a new family of lifetime distributions is introduced to help researchers model different types of data sets. Furthermore, the maximum likelihood method was used in estimating the model's parameters.
Amjad Al-Nasser, Ahmad Hanandeh
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source