Results 91 to 100 of about 2,082,520 (309)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Isolation and characterization of acetylated LM-pectins extracted from okra pods [PDF]

, 2014
Pectin was isolated by aqueous extraction at pH 6.0 or 2.0 from okra (Abelmoschus esculentus L.) pods. An isolation protocol was designed to extract pectin and to study the influence of the extraction pH on their composition and physicochemical ...
A.P. Laws, Anger, Bleton, Bradford, Bédouet, Chatjigakis, Cheng, Cozzolino, Dea, Dubois, Ele-Ekouna, Endreß, Filisetti-Cozzi, Georgiadis, Gnanasambandam, Grasdalen, Happi Emaga, Houben, Hwang, Immerzeel, K. Alba, Kamnev, Kjøniksen, Kontogiorgos, Koštálová, Kravtchenko, Kurita, Lapasin, Leroux, Levigne, MacDougall, May, McComb, Morris, Morris, Morris, Muralikrishna, M’sakni, Nakamura, Ndjouenkeu, Pagan, Ptitchkina, Rombouts, Rosenbohm, Samavati, Schultz, Sengkhamparn, Sengkhamparn, Sengkhamparn, Sudhakar, Tamaki, Thibault, Tomada, Turquois, V. Kontogiorgos, Vincken, Voragen, Yapo, Yapo   +58 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Optimization of Process Parameters for Pecan oil Extraction

Agrociencia Uruguay
In recent years, interest in obtaining oils through pressing technologies has intensified. The extraction process affects the nutritional quality, flavors, and oxidative stability of the oils.
Marina Panozzo, Luz Marina Zapata, Andrea Biolatto, Santiago Araujo, Francisco Federico, Exequiel Rodger, Romina Fabre   +6 more
doaj   +1 more source

Investigation of the Application of a New Method of Extraction Intensification of Pectin Substances From a Beet Pulp [PDF]

, 2018
The aim of research is studying a new method for intensifying extraction of pectin substances during acid extraction of pectin-containing raw materials.
Chervonyi, V. (Vitalii), Deynichenko, G. (Gregoriy), Dmytrevskyi, D. (Dmytro), Guzenko, V. (Vasyl), Kolisnichenko, T. (Tatiana), Melnik, O. (Olga), Nykyforov, R. (Radion), Omelchenko, A. (Aleksandr), Simakova, O. (Olga)   +8 more
core   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Liquid chromatography tandem mass spectrometry analysis of synthetic coccidiostats in eggs [PDF]

, 2017
Coccidiostats are synthetic drugs administered to animals, especially to poultry, to cure coccidiosis. In this paper, we present a selective liquid chromatography-tandem mass spectrometry (LC-MS/MS) method to analyze residues of five synthetic ...
Buiarelli, Francesca, DI FILIPPO, Patrizia, Giannetti, Luigi, Neri, Bruno, Pomata, Donatella, Rago, Daniela, Riccardi, Carmela   +6 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Optimization of drilling parameters for coal seam gas extraction considering fluid–solid coupling and field application

Energy Science & Engineering
Affect gas extraction efficiency to find out the optimum well location parameters, based on the gray correlation analysis of borehole diameter, borehole spacing, and extraction pressure three boreholes parameters that influence efficiency of gas ...
Wang Yang, Xu Mengtang, Kong Dezhong, Shang Yuqi, Li Fei   +4 more
doaj   +1 more source

Electrical parameters extraction of PV modules using artificial hummingbird optimizer. [PDF]

Sci Rep, 2023
El-Sehiemy R, Shaheen A, El-Fergany A, Ginidi A.   +3 more
europepmc   +1 more source