Results 101 to 110 of about 1,919,678 (273)

Non-Parametric Maximum Likelihood Density Estimation and Simulation-Based Minimum Distance Estimators [PDF]

open access: yes, 2010
Indirect inference estimators (i.e., simulation-based minimum distance estimators) in a parametric model that are based on auxiliary non-parametric maximum likelihood density estimators are shown to be asymptotically normal.
Gach, Florian, Pötscher, Benedikt M.
core   +2 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Parametric versus non-parametric simulation

open access: yes, 2014
Most of ex-ante impact assessment policy models have been based on a parametric approach. We develop a novel non-parametric approach, called Inverse DEA. We use non parametric efficiency analysis for determining the farm’s technology and behaviour. Then, we compare the parametric approach and the Inverse DEA models to a known data generating process ...
Dupeux, Bérénice, Buysse, Jeroen
openaire   +4 more sources

Model application in evaluating land suitability for OAK and PINE forest plantations in Northeast of Iran

open access: yesGeology, Ecology, and Landscapes, 2020
In the present study, land suitability evaluation by parametric and AHP approaches was evaluated for two forest plantations including oak (Quercus robur) and pine (Pinus silvestris) in Toroq watershed, northeast of Iran. Over 416 grid points were studied
Amin Gholizadeh   +2 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Optical parametric generation in periodically poled KTiOPO4 via extended phase matching [PDF]

open access: yes, 2007
We report an experimental demonstration of optical parametric generation in a periodically poled KTiOPO4 crystal based on the principle of mirrorless optical parametric oscillation.
Psaltis, Demetri   +3 more
core  

Collapse and revival of oscillations in a parametrically excited Bose-Einstein condensate in combined harmonic and optical lattice trap

open access: yes, 2011
In this work, we study parametric resonances in an elongated cigar-shaped BEC in a combined harmonic trap and a time dependent optical lattice by using numerical and analytical techniques.
A. Bhattacherjee   +24 more
core   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

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