Results 81 to 90 of about 1,919,678 (273)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Wolfenstein parametrization reexamined [PDF]
Physical Review D, 1995 5 Latex pages including a figure; Two references are ...
openaire +3 more sources
Parametric vs. non-parametric methods for estimating option implied risk-neutral densities: the case of the exchange rate Mexican peso – US dollar. [PDF]
This research paper presents statistical comparisons between two methods that are commonly used to estimate option implied Risk-Neutral Densities (RND). These are: 1) mixture of lognormals (MXL); and, 2) volatility function technique (VFT). The former is
Guillermo Benavides Perales +1 more
core
, 2018 In lieu of an abstract, here is the entry\u27s first paragraph: Robust statistics are procedures that maintain nominal Type I error rates and statistical power in the presence of violations of the assumptions that underpin parametric inferential ...
Blaine, Bruce E
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Lubricants, 2018 Hydraulic, reciprocating, polymeric seals are met in many engineering applications and are critical components for mechanism and machine reliability in industries including the automotive, marine, and aerospace industries.
George K. Nikas
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
PlasmaThis paper describes a new practical numerical model for the calculation of lateral electromagnetic (EM) loads in tokamaks during asymmetric vertical displacement events (AVDEs). The model combines key features of two recently reported trial models while
Sergey Sadakov +6 more
doaj +1 more source
Hypothesis testing for two population means: parametric or non-parametric test?
, 2019 The parametric Welch $t$-test and the non-parametric Wilcoxon-Mann-Whitney test are the most commonly used two independent sample means tests. More recent testing approaches include the non-parametric, empirical likelihood and exponential empirical ...
Alenazi, Abdulaziz +3 more
core +1 more source