Results 121 to 130 of about 140,769 (264)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
GDP nowcasting with ragged-edge data: a semi-parametric modeling [PDF]
This paper formalizes the process of forecasting unbalanced monthly datasets in order to obtain robust nowcasts and forecasts of quarterly gross domestic product (GDP) growth rate through a semi-parametric modeling.
Patrick Rakotomarolahy +2 more
core
Finite Element Analysis of L-shaped Double Steel Plate Composite Shear Wall
工程科学与技术, 2021 The double steel plate composite shear wall structure is widely used in the high-rise buildings due to its advantages of good integrity, high rigidity and high shear bearing capacity.
Jian LI +3 more
doaj
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Semi-parametric Models for Satisfaction with Income
An overview is presented of some parametric and semi-parametric models, estimators, and specification tests that can be used to analyze ordered response variables.In particular, limited dependent variable models that generalize or-dered probit are ...
Bellemare, C. +2 more
core
Parametric Evaluation of Morphed Wing Effectiveness
AerospaceRecently, continuous improvements in aircraft manoeuvrability and fuel consumption reduction have led researchers to investigate additional wing configurations based on morphing concepts.
Guido Servetti +2 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Parametric Statistics and the General Linear Model [PDF]
, 2014 Too many students acquire statistical knowledge and techniques independent of each other. The purpose of this paper is to illustrate the many connections mathematically between parametric statistics and the General Linear Model.
John A Rochowicz Jr
core
Open EngineeringOne of the key variables that can affect energy consumption in a building is the shape of the structure. The current study aims to balance the using solar radiation (lighting, heating, and cooling) and energy consumption by analyzing climatic factors ...
Alhilo Intisar A. +1 more
doaj +1 more source
EngThis study examines a top-chord-free open-web steel-truss composite floor in which the concrete slab functionally replaces the traditional top chord and works jointly with vertical square-tube web members and a square-tube bottom chord.
Jianshe Xu +3 more
doaj +1 more source