Results 81 to 90 of about 552,495 (266)
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Modification of the Prony method for information-measuring systems
Background. It is proposed to use a modified Prony algorithm based on a vector overdetermined model in problems of determining the parameters of complex-shaped signals. It is compared with the classical Prony method. The advantage of the modified Prony
N.V. Myasnikova +3 more
doaj +1 more source
Parametric models in vector spaces are shown to possess an associated linear map. This linear operator leads directly to reproducing kernel Hilbert spaces and affine- / linear- representations in terms of tensor products. From the associated linear map analogues of covariance or rather correlation operators can be formed.
Matthies, Hermann, Ohayon, Roger
openaire +3 more sources
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Analytical solution for mechanical behavior characterization of sandy dolomite tunneling
Tunneling in sandy dolomite strata often faces hazards such as collapse, water inrush, and water–sand inrush, seriously threatening the safety of tunnel construction.
Di Sun +19 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A Parametrized Analysis of Algorithms on Hierarchical Graphs
Hierarchical graphs are used in order to describe systems with a sequential composition of sub-systems. A hierarchical graph consists of a vector of subgraphs. Vertices in a subgraph may “call” other subgraphs. The reuse of subgraphs, possibly in a nested way, causes hierarchical graphs to be exponentially more succinct than equivalent flat graphs ...
Rachel Faran, Orna Kupferman
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
This study presents a novel dual-band microstrip antenna operating at 28/38 GHz, which is designed for fifth generation (5G) and next-generation communications.
Bilal Okan Icmez, Cetin Kurnaz
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

