Results 81 to 90 of about 140,769 (264)
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Parametric min-cuts analysis in a network
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Yash P. Aneja +2 more
openaire +2 more sources
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Comparing parametric and semi-parametric approaches for bayesian cost-effectiveness analyses in health economics [PDF]
We consider the problem of assessing new and existing technologies for their cost-effectiveness in the case where data on both costs and effects are available from a clinical trial, and we address it by means of the cost-effectiveness acceptability curve.
Andrea Tancredi, Caterina Conigliani
core
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
The normal operation of spaceborne parabolic cylindrical reflector antennas under various operating conditions relies on maintaining the root mean square (RMS) of the reflector surface’s deformation within reasonable limits.
Peiyuan Kan +4 more
doaj +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
On parametric solution of fault detection problems
We discuss the solution of the fault detection problem in presence of parametric uncertainties. The basic approach is an extension of the nullspace method for constant systems to the case of linear parameter varying (LPV) models.
Andras Varga, Varga, A.
core +1 more source
Some problems in numerical analyses of basal upheaval stability of foundation pits
Numerical analysis of basal upheaval stability of foundation pits is a very important method in researches on deep excavation engineering, which is in the initial development stage and is of important issues remained to be understood and solved. Based on
WANG Cheng-hua , LI Ya-jie
doaj +1 more source

