Results 111 to 120 of about 14,108,193 (356)

Parametric bus stop shelters in rural areas: Automating custom design [PDF]

, 2011
Jaroslav Hulin, Jiri Pavlícek, Martin Kaftan   +2 more
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

A Parametric Study of the Effect of Trees on Residential Footing Design on Expansive Soils [PDF]

, 2023
Xi Sun, Jie Li
openalex   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Parametric Design of a 3D-Printed Removable Common-Mode Trap for Magnetic Resonance Imaging. [PDF]

IEEE MTT-S Int Microw Biomed Conf, 2023
Narongrit FW, Ramesh TV, Rispoli JV.
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Finite Element Parametric Design of Hallux Valgus Orthosis Based on Orthogonal Analysis. [PDF]

Orthop Surg, 2023
Tang Z, Wu Y, Bao W, Chen X, Zhang D, Korotkov AN, Zheng W, Gu S.   +7 more
europepmc   +1 more source

Multi-Objective Parametric Optimization Design for Mirrors Combined with Non-Dominated Sorting Genetic Algorithm [PDF]

, 2023
Lu Sun, Zhang Bao, Ping Wang, Zhihong Gan, Pengpeng Han, Yijian Wang   +5 more
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

A Review of the Evolution of Research on Proposals for Bamboo Culms Connections in Structural Systems

BioResources, 2023
Structural systems built from raw bamboo have been used for years due to its highly renewable characteristics, versatility, and abundance in various countries, e.g., China, Indonesia, all over South America, and especially Brazil. It is also considered a
Bruna A. Gaffuri, Jorge D. M. Moura, Juliana C. Barbosa, Marcelo H. F. de Medeiros, Andressa Gobbi, Ricardo D. Silva   +5 more
doaj