Results 101 to 110 of about 9,961,576 (291)

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Tangibility and intangibility of ephemerality in exhibition: a study of parametrically designed booth pavilions

Journal of Asian Architecture and Building Engineering
The purpose of this study is to evaluate the shape and geometry of architectural enclosures for use as exhibition booths. The majority of enclosures utilized for booth design by exposition organizers are often made up of planar surfaces and are simple ...
Mohafiz Riyaz, Madhumathi Anbu
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Parametric Design and Prototyping of a Low-Power Planar Biped Robot. [PDF]

Biomimetics (Basel), 2023
Şafak KK, Baturalp TB, Bozkurt S.
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Parametric Landscape Facilities Aesthetic Design Method Based on SOR Model and Hybrid Kansei Engineering: A Case of Landscape Corridors

Buildings
Parametric design stands out in contemporary landscape facilities design with its distinctive beauty sense. However, understanding this beauty sense and establishing an aesthetic design method is one of the problems needed to be solved.
Xuan-Hui Xie, Shilin Guo, Huiran Yan, Yunpeng Xu, Hongyang Zhu, Peilin Hong, Yexin Chen   +6 more
doaj   +1 more source

Parametric Design of a 3D-Printed Removable Common-Mode Trap for Magnetic Resonance Imaging. [PDF]

IEEE MTT-S Int Microw Biomed Conf, 2023
Narongrit FW, Ramesh TV, Rispoli JV.
europepmc   +1 more source

Open Parametric Design System for Early Design Phases

, 2006
This paper describes an investigation into an open framework for parametric design systems for early design phases. The framework supports the insertion of new modular parametric design components, offering new parametric design solutions.
Crawford, John R., Trinidad, Gerardo S., Drogemuller, Robin, Schevers, Hans A. J.   +3 more
core  

Parametric Design Program: Enhancing Architects’ Early-Stage Design Decision-making

University students including both undergraduates and graduates face numerous challenges in their living environments, particularly in university-provided dormitories or off-campus rental accommodations.
Zhengyang, Ou
core   +1 more source