Results 101 to 110 of about 354,890 (263)

Modular design workflow for 3D printable bioresorbable patient-specific bone scaffolds: extended features and clinical validation

Frontiers in Bioengineering and Biotechnology
A previously in-house developed patient-specific scaffold design workflow was extended with new features to overcome several limitations and to broaden its adaptability to diverse bone defects, thereby enhancing its fit for routine clinical use.
Buddhi Herath, Buddhi Herath, Buddhi Herath, Buddhi Herath, Markus Laubach, Markus Laubach, Markus Laubach, Markus Laubach, Sinduja Suresh, Sinduja Suresh, Sinduja Suresh, Sinduja Suresh, Beat Schmutz, Beat Schmutz, Beat Schmutz, Beat Schmutz, J. Paige Little, J. Paige Little, J. Paige Little, J. Paige Little, Prasad K. D. V. Yarlagadda, Prasad K. D. V. Yarlagadda, Prasad K. D. V. Yarlagadda, Heide Delbrück, Frank Hildebrand, Dietmar W. Hutmacher, Dietmar W. Hutmacher, Dietmar W. Hutmacher, Dietmar W. Hutmacher, Marie-Luise Wille, Marie-Luise Wille, Marie-Luise Wille, Marie-Luise Wille   +32 more
doaj   +1 more source

The Adaptive Power of Ammophila arenaria: Biomimetic Study, Systematic Observation, Parametric Design and Experimental Tests with Bimetal. [PDF]

Polymers (Basel), 2021
Andrade TAB, Beirão JNDC, Arruda AJV, Cruz C.   +3 more
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Correction: Andrade et al. The Adaptive Power of Ammophila arenaria: Biomimetic Study, Systematic Observation, Parametric Design and Experimental Tests with Bimetal. Polymers 2021, 13, 2554. [PDF]

Polymers (Basel), 2023
Andrade TAB, Beirão JNDC, Arruda AJV, Cruz C.   +3 more
europepmc   +1 more source

Designing Parametric Matter [PDF]

, 2019
This paper presents a series of design experiments that seek to move beyond today’s computer-aided design and computer-aided manufacture (CAD/CAM) technologies and investigates alternative material practices based on programmable self-assembly. When using CAD software, 3D designs can be rendered extremely flexible and adaptable such that changes to an ...
Blaney, Adam, Alexander, Jason, Dunn, Nick, Richards, Daniel   +3 more
openaire  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Parametric Modeling and Column Grid Analysis of the Sakyamuni Pagoda at Fogong Temple: Insights into the Yingxian Wooden Pagoda

Buildings
The Sakyamuni Pagoda of Fogong Temple, also known as the Yingxian Wooden Pagoda or the Wooden Pagoda of Ying County, is China’s oldest and tallest wooden pagoda.
Daoru Wang, Stephanie Yanqiu Li, Ruguan Liu, Jianxin Hu, Ang Wang   +4 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source