Results 121 to 130 of about 1,068,788 (332)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

行星锥盘式无级变速器参数化设计系统的开发

Jixie chuandong, 2008
The strategy of parametric design and the choice of development tools are introduced,and the output plate of the planetary bevel-type continuously variable transmission（CVT）as example,the process of parametric design system development of the CVT is ...
周春国, 程伟华, 刘凯
doaj  

Finite Element Parametric Design of Hallux Valgus Orthosis Based on Orthogonal Analysis. [PDF]

Orthop Surg, 2023
Tang Z, Wu Y, Bao W, Chen X, Zhang D, Korotkov AN, Zheng W, Gu S.   +7 more
europepmc   +1 more source

Design and characterization of a lumped element single-ended superconducting microwave parametric amplifier with on-chip flux bias line

, 2013
We demonstrate a lumped-element Josephson parametric amplifier, using a single-ended design that includes an on-chip, high-bandwidth flux bias line. The amplifier can be pumped into its region of parametric gain through either the input port or through ...
Barends, Rami, Bochmann, Joerg, Chen, Yu, Chen, Zijun, Chiaro, Ben, Cleland, Andrew, Dunsworth, Andrew, Jeffrey, Evan, Kelly, Julian, Martinis, John, Megrant, Anthony, Mutus, Josh, Neill, Charles, O'Malley, Peter, Roushan, Pedram, Sank, Daniel, Siddiqi, Irfan, Vainsencher, Amit, Vijayaraghavan, Rajamani, Wenner, James, White, Ted   +20 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

DFMA-oriented modular and parametric design and secondary splitting of vertical PC components. [PDF]

Sci Rep, 2023
Dong D, Zou Y, Pan H, Zhou G, Feng Y, Tang Y.   +5 more
europepmc   +1 more source

Extended parametric representation of compressor fans and turbines. Volume 1: CMGEN user's manual [PDF]

A modeling technique for fans, boosters, and compressors has been developed which will enable the user to obtain consistent and rapid off-design performance from design point input.
Converse, G. L., Giffin, R. G.
core   +1 more source

Quick calculation method for fluid flow through duct systems [PDF]

, 1970
Conditions for subsonic compressible flow through duct systems are quickly and easily calculated using compact series of curves showing dimensionless parametric functions of Mach number and specific heat ratio.
Scott, L. R., Jr.
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

A Review of the Evolution of Research on Proposals for Bamboo Culms Connections in Structural Systems

BioResources, 2023
Structural systems built from raw bamboo have been used for years due to its highly renewable characteristics, versatility, and abundance in various countries, e.g., China, Indonesia, all over South America, and especially Brazil. It is also considered a
Bruna A. Gaffuri, Jorge D. M. Moura, Juliana C. Barbosa, Marcelo H. F. de Medeiros, Andressa Gobbi, Ricardo D. Silva   +5 more
doaj