Results 121 to 130 of about 14,108,193 (356)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

High-fidelity surrogate models for parametric shape design in microfluidics [PDF]

, 2020
Luca Borchini
openalex   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

行星锥盘式无级变速器参数化设计系统的开发

Jixie chuandong, 2008
The strategy of parametric design and the choice of development tools are introduced,and the output plate of the planetary bevel-type continuously variable transmission（CVT）as example,the process of parametric design system development of the CVT is ...
周春国, 程伟华, 刘凯
doaj  

Active Strategies Based on Parametric Design for Applying Shading Structures

Applied Sciences
This study aimed to increase the energy independence of buildings by utilizing solar energy to produce renewable energy. The subject of this study was a shading structure installed in an outdoor space to provide solar energy. Solar panels were applied to
Ho-Soon Choi
doaj   +1 more source

Helicopter Main Rotor Blade Parametric Design for a Preliminary Aerodynamic Analysis Supported by CFD or Panel Method. [PDF]

Materials (Basel), 2022
Kocjan J, Kachel S, Rogólski R.
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Modular design workflow for 3D printable bioresorbable patient-specific bone scaffolds: extended features and clinical validation

Frontiers in Bioengineering and Biotechnology
A previously in-house developed patient-specific scaffold design workflow was extended with new features to overcome several limitations and to broaden its adaptability to diverse bone defects, thereby enhancing its fit for routine clinical use.
Buddhi Herath, Buddhi Herath, Buddhi Herath, Buddhi Herath, Markus Laubach, Markus Laubach, Markus Laubach, Markus Laubach, Sinduja Suresh, Sinduja Suresh, Sinduja Suresh, Sinduja Suresh, Beat Schmutz, Beat Schmutz, Beat Schmutz, Beat Schmutz, J. Paige Little, J. Paige Little, J. Paige Little, J. Paige Little, Prasad K. D. V. Yarlagadda, Prasad K. D. V. Yarlagadda, Prasad K. D. V. Yarlagadda, Heide Delbrück, Frank Hildebrand, Dietmar W. Hutmacher, Dietmar W. Hutmacher, Dietmar W. Hutmacher, Dietmar W. Hutmacher, Marie-Luise Wille, Marie-Luise Wille, Marie-Luise Wille, Marie-Luise Wille   +32 more
doaj   +1 more source

Parametric Design Studies of Mass-Related Global Warming Potential and Construction Costs of FRP-Reinforced Concrete Infrastructure. [PDF]

Polymers (Basel), 2022
Preinstorfer P, Huber T, Reichenbach S, Lees JM, Kromoser B.   +4 more
europepmc   +1 more source

Proper Generalized Decomposition for Parametric Study and Material Distribution Design of Multi-Directional Functionally Graded Plates Based on 3D Elasticity Solution [PDF]

, 2021
Mohammad Javad Kazemzadeh‐Parsi, Francisco Chinesta, Amine Ammar   +2 more
openalex   +1 more source