Results 111 to 120 of about 606,425 (294)

Semi-parametric Estimation of Biomarker Age Trends with Endogenous Medication Use in Longitudinal Data. [PDF]

Obs Stud, 2021
Spieker AJ, Delaney JAC, McClelland RL.
europepmc   +1 more source

Efficient and robust estimation for financial returns: an approach based on q-entropy [PDF]

We consider a new robust parametric estimation procedure, which minimizes an empirical version of the Havrda-Charv_at-Tsallis entropy. The resulting estimator adapts according to the discrepancy between the data and the assumed model by tuning a single ...
Davide Ferrari, Sandra Paterlini
core  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

The Detection Method of the Tobit Model in a Dataset

Stats
This article proposes an extension of detection methods for the Tobit model by generalizing existing approaches from cases with known parameters to more realistic scenarios where the parameters are unknown.
El ouali Rahmani, Mohammed Benmoumen
doaj   +1 more source

Parametric estimation of gyrotactic microorganism hybrid nanofluid flow between the conical gap of spinning disk-cone apparatus. [PDF]

Sci Rep, 2022
Alrabaiah H, Bilal M, Khan MA, Muhammad T, Legas EY.   +4 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Experimental and Ray-Tracing-Based Comparison of Virtual-Array and Mechanically Scanned Directional Channel Sounding in Indoor Millimeter-Wave Channels

IEEE Access
This paper presents a systematic experimental and simulation-based comparison of two fundamentally different millimetre-Wave (mmW) double-directional channel sounding strategies in a controlled indoor line-of-sight (LoS) environment over the 26–40
Jose-Maria Molina-Garcia-Pardo, Davy P. Gaillot, Maria-Teresa Martinez Ingles, Juan Pascual-Garcia, Ismail Ben Mabrouk   +4 more
doaj   +1 more source

Non-parametric estimation of reference adjusted, standardised probabilities of all-cause death and death due to cancer for population group comparisons. [PDF]

BMC Med Res Methodol, 2022
Rutherford MJ, Andersson TM, Myklebust TÅ, Møller B, Lambert PC.   +4 more
europepmc   +1 more source

Bednets, Information and Malaria in Orissa [PDF]

This paper studies the identification and estimation of a basic model of technology adoption using specifcally collected information on subjective beliefs and expectations to identify key model parameters.
Alessandro Tarozzi, Aprajit Mahajan, Brian Blackburn, Joanne Yoong   +3 more
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source