Results 131 to 140 of about 2,181,691 (306)

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Parametric Estimation of Reference Signal Intensity for Semi-Quantification of Tau Deposition: A Flortaucipir and [¹⁸F]-APN-1607 Study. [PDF]

Front Neurosci, 2021
Zhang H, Wang M, Lu J, Bao W, Li L, Jiang J, Zuo C, and Alzheimer’s Disease Neuroimaging Initiative.   +7 more
europepmc   +1 more source

Estimation and model specification testing in nonparametric and semiparametric econometric models [PDF]

This paper considers two classes of semiparametric nonlinear regression models, in which nonlinear components are introduced to reflect the nonlinear fluctuation in the mean.
King, Maxwell, Gao, Jiti
core  

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Comparison of parametric, semi-parametric and nonparametric two-stage estimation methods for copula models

, 2009
To compare the parametric, semi-parametric and nonparametric two-stage estimation methods. Based on a simulation study, we would like to study the robustness of the estimation of the dependence vector against misspecification of the marginal survival ...
Abebe, Haftom Temesgen
core   +1 more source

The Influence of Using Soil Particles Percentage in Comparison with Geometric Characteristics of Soil Particles on the Accuracy of the Pedotransfer Equations and the Critical Point of SWRC

علوم آب و خاک, 2019
Soil water retention curve (SWRC) reflects different states of soil moisture and describes quantitative characteristics of the unsaturated parts of the soil. Direct measurement of SWRC is time-consuming, difficult and costly.
A. Javidi, A. Shabani, M. J. Amiri
doaj  

Parametric estimation of reference signal intensity in the quantification of amyloid-beta deposition: an ¹⁸F-AV-45 study. [PDF]

Quant Imaging Med Surg, 2021
Wang M, Yan Z, Zhang H, Lu J, Li L, Yu J, Wang J, Matsuda H, Zuo C, Jiang J, Alzheimer’s Disease Neuroimaging Initiative.   +10 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Parametric Estimation under Long-Range Dependence [PDF]

Parametric estimation is discussed in a variety of models exhibiting long-range dependence.Parametric estimation, long-range dependence.
Peter M Robinson, Liudas Giraitis
core  

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source