Results 111 to 120 of about 4,338,901 (297)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

new test for the parametric form of the variance function in nonparametric regression [PDF]

open access: yes
In the common nonparametric regression model the problem of testing for the parametric form of the conditional variance is considered. A stochastic process based on the difference between the empirical processes obtained from the standardized ...
Dette, Holger, van Keilegom, Ingrid
core  

One for all and all for one: regression checks with many regressors [PDF]

open access: yes
We develop a novel approach to build checks of parametric regression models when many regressors are present, based on a class of sufficiently rich semiparametric alternatives, namely single-index models.
Patilea, Valentin, Lavergne, Pascal
core   +2 more sources

Robust Semiparametric Optimal Testing Procedure for Multiple Normal Means

open access: yesJournal of Probability and Statistics, 2012
In high-dimensional gene expression experiments such as microarray and RNA-seq experiments, the number of measured variables is huge while the number of replicates is small.
Peng Liu, Chong Wang
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Introduction to Robust Estimation and Hypothesis Testing

open access: yes, 2012
This revised book provides a thorough explanation of the foundation of robust methods, incorporating the latest updates on R and S-Plus, robust ANOVA (Analysis of Variance) and regression.
Wilcox, Rand R.
core  

Statistical group comparison of diffusion tensors via multivariate hypothesis testing

open access: yes, 2007
Diffusion tensor imaging (DTI) provides a powerful tool for identifying white matter (WM) alterations in clinical populations. The prevalent method for group-level analysis of DTI is statistical comparison of the diffusion tensor fractional anisotropy ...
Wisco, J.J.   +3 more
core   +1 more source

eco: R Package for Ecological Inference in 2x2 Tables

open access: yesJournal of Statistical Software, 2011
eco is a publicly available R package that implements the Bayesian and likelihood methods proposed in Imai, Lu, and Strauss (2008b) for ecological inference in 2 X 2 tables as well as the method of bounds introduced by (Duncan and Davis 1953).
Kosuke Imai, Ying Lu, Aaron Strauss
doaj  

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

A note on the Bandwidth choice when the null hypothesis is semiparametric [PDF]

open access: yes
This work presents a tool for the additivity test. The additive model is widely used for parametric and semiparametric modeling of economic data. The additivity hypothesis is of interest because it is easy to interpret and produces reasonably fast ...
Jorge Barrientos Marín
core  

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