Results 121 to 130 of about 4,448,452 (248)

THE FORMAL LOGIC OF TESTING STRUCTURAL CHANGE IN MEAT DEMAND: A METHODOLOGICAL ANALYSIS [PDF]

In the past two decades, the profession has expended valuable resources testing structural change in meat demand with mixed results. Overlooked to date is a fundamental methodological problem that transcends all of the methods of testing for structural ...
Davis, George C.
core  

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Testing informative hypotheses in SEM increases power: An illustration contrasting classical hypothesis testing with a parametric bootstrap approach

, 2011
In the present paper, the application of a parametric bootstrap procedure, as described by van de Schoot, Hoijtink, and Deković (2010), will be applied to demonstrate that a direct test of an informative hypothesis offers more informative results ...
Dagmar Strohmeier, Van de Schoot, R., Rens van de Schoot, Strohmeier, D., Afd Methoden en Statistieken, Methodology and Statistics for the Behavioural and Social Sciences   +5 more
core   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Estimation and model specification testing in nonparametric and semiparametric econometric models [PDF]

This paper considers two classes of semiparametric nonlinear regression models, in which nonlinear components are introduced to reflect the nonlinear fluctuation in the mean.
King, Maxwell, Gao, Jiti
core  

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Statistical analysis of microarrays [PDF]

, 2005
Microarray statistical analysis involves thousands of hypothesis tests to consider at the same time. Empirical Bayes methods which are well-suited for large scale inference problems seem to be the most appropriate approach for microarray data.
Mouzaki, Daphne
core  

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Pengaruh penerapan model pembelajaran problem based learning (PBL) terhadap hasil belajar IPAS Siswa Kelas IV SD N Randusari Yogyakarta

Indonesian Journal of Learning and Educational Studies
This study aims to determine the effect of the application of the Problem Based Learning (PBL) learning model on the learning outcomes of IPAS fourth grade students of SD N Randusari Yogyakarta.
Prima Desta Ayulestari, Murniningsih Murniningsih, Bestiana Nizhomi, Ida Megawati   +3 more
doaj   +1 more source

Approaches for the Joint Evaluation of Hypothesis Tests: Classical Testing, Bayes Testing, and Joint Confirmation [PDF]

The occurrence of decision problems with changing roles of null and alternative hypotheses has increased interest in extending the classical hypothesis testing setup.
Kunst, Robert M.
core