Results 161 to 170 of about 21,287 (304)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Proving Program Invariance and Termination by Parametric Abstraction, Lagrangian Relaxation and Semidefinite Programming Patrick Cousot

, 2005
In order to verify semialgebraic programs, we automatize the Floyd/Naur/Hoare proof method. The main task is to automatically infer valid invariants and rank functions. First we express the program semantics in polynomial form.
Patrick Cousot, Ecole Normale Superieure
core  

Regime-Dependent Elastic Displacement in Bio-Inspired Parametric Kirigami Structures: An Experimental Study of Geometric Parameter Effects. [PDF]

Biomimetics (Basel)
Mokhtar TH, Bakr SM, Khashman QR.
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Contrast-enhanced ultrasound time-intensity curve-assisted parametric imaging: a possible effective tool for differential diagnosis of thyroid nodules. [PDF]

Gland Surg
Wang K, Lan J, Zhong C, Yang S, Huang S, Zhou Y, Yang X.   +6 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Critical insight on 'respiratory swallow coordination training using bimodal signal biofeedback for patients with post-stroke dysphagia: a letter to editor. [PDF]

Ann Med
Kumar P, Kanika.
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Causality between GDP, Energy and Coal Consumption in India, 1970-2011: A Non-parametric Bootstrap Approach

, 2013
The aim of this paper is to examine the direction of causality between real GDP on the one hand and final energy and coal consumption on the other in India, for the period from 1970 to 2011.
Rohin Anhal
core  

Critical impact of automobile industry with advanced decision support system and Aczél-Alsina Hammy mean operators. [PDF]

Sci Rep
Hussain A, Ullah K, Ali Z, Pamucar D.
europepmc   +1 more source