Results 81 to 90 of about 14,495,757 (308)
When the end leakage flux or end leakage inductance cannot be ignored in a permanent magnet (PM) machine (e.g., a PM machine with a short axial length), the analysis of the machine is a time-consuming three-dimensional (3-D) issue.
Xianbao Chen +4 more
doaj +1 more source
Parametric model-based clustering [PDF]
Parametric, model-based algorithms learn generative models from the data, with each model corresponding to one particular cluster. Accordingly, the model-based partitional algorithm will select the most suitable model for any data object (Clustering step}, and will recompute parametric models using data specifically from the corresponding clusters ...
Nikulin, Vladimir, Smola, Alexander
openaire +4 more sources
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
The variety of treatments available makes it difficult to determine whether a treatment would be effective for an individual case in advanced‐stage hepatocellular carcinoma.
Masashi Ninomiya +23 more
doaj +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Comparative models in customer base analysis: parametric model and observation-driven model
This study conducts a dynamic rolling comparison between the Pareto/NBD model (parametric model) and machine learning algorithms (observation-driven models) in customer base analysis, which the literature has not comprehensively investigated before.
Shao-Ming Xie
doaj +1 more source
Semi-parametric Models for Satisfaction with Income [PDF]
An overview is presented of some parametric and semi-parametric models, estimators, and specification tests that can be used to analyze ordered response variables.In particular, limited dependent variable models that generalize or-dered probit are ...
Bellemare, C. +2 more
core
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Improving Parametric Mortgage Prepayment Models with Non-parametric Kernel Regression [PDF]
Developing a good prepayment model is a central task in the valuation of mortgages and mortgage-backed securities but conventional parametric models often have bad out-of-sample predictive ability.
Michael Marschoun +2 more
core

