Results 81 to 90 of about 14,495,757 (308)

Investigation of the End Leakage Flux in Fractional Slot Concentrated-Winding Surface Permanent Magnet Machines

open access: yesIEEE Access, 2019
When the end leakage flux or end leakage inductance cannot be ignored in a permanent magnet (PM) machine (e.g., a PM machine with a short axial length), the analysis of the machine is a time-consuming three-dimensional (3-D) issue.
Xianbao Chen   +4 more
doaj   +1 more source

Parametric model-based clustering [PDF]

open access: yesSPIE Proceedings, 2005
Parametric, model-based algorithms learn generative models from the data, with each model corresponding to one particular cluster. Accordingly, the model-based partitional algorithm will select the most suitable model for any data object (Clustering step}, and will recompute parametric models using data specifically from the corresponding clusters ...
Nikulin, Vladimir, Smola, Alexander
openaire   +4 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

A New Model to Predict Survival Time in Patients With Hepatocellular Carcinoma With BCLC Advanced Stage

open access: yesCancer Medicine
The variety of treatments available makes it difficult to determine whether a treatment would be effective for an individual case in advanced‐stage hepatocellular carcinoma.
Masashi Ninomiya   +23 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Comparative models in customer base analysis: parametric model and observation-driven model

open access: yesJournal of Business Economics and Management, 2020
This study conducts a dynamic rolling comparison between the Pareto/NBD model (parametric model) and machine learning algorithms (observation-driven models) in customer base analysis, which the literature has not comprehensively investigated before.
Shao-Ming Xie
doaj   +1 more source

Semi-parametric Models for Satisfaction with Income [PDF]

open access: yes
An overview is presented of some parametric and semi-parametric models, estimators, and specification tests that can be used to analyze ordered response variables.In particular, limited dependent variable models that generalize or-dered probit are ...
Bellemare, C.   +2 more
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Improving Parametric Mortgage Prepayment Models with Non-parametric Kernel Regression [PDF]

open access: yes
Developing a good prepayment model is a central task in the valuation of mortgages and mortgage-backed securities but conventional parametric models often have bad out-of-sample predictive ability.
Michael Marschoun   +2 more
core  

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