Results 61 to 70 of about 2,932,686 (296)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A Smart Parametric 3D Printing Hand Assistive Device With a Practical Physically Intervention Feedback Based on the Embedded IMU Sensor

IEEE Access, 2021
Assistive devices are one of the crucial medical instruments for rehabilitation. Customized designs are required to match the geometry and dimensions of the affected sites of human bodies.
I-Jan Wang, Bor-Shing Lin, Chi-Ming Wu, Chia-Hung Yeh, Shu-Ting Hsu   +4 more
doaj   +1 more source

Comparison of Parametric and Semi-Parametric Binary Response Models [PDF]

SSRN Electronic Journal, 2013
A Bayesian semi-parametric estimation of the binary response model using Markov Chain Monte Carlo algorithms is proposed. The performances of the parametric and semi-parametric models are presented. The mean squared errors, receiver operating characteristic curve, and the marginal effect are used as the model selection criteria.
Xiangjin Shen, Shiliang Li, Hiroki Tsurumi   +2 more
openaire   +2 more sources

The ideology of parametric design [PDF]

, 2023
Parametric design approach is widely encountered in today's design practice and education. With the latest point reached in computer software, the development and awareness of parametric design tools is increasing.
Taştan, Zehra
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Frequency conversion based on three-wave parametric solitons [PDF]

, 2010
Parametric three-wave mixing in quadratic nonlinear crystals provides a versatile means of achieving widely tunable frequency conversion of laser light, thus permitting a substantial extension of the wavelength coverage of laser sources across broad ...
Degasperis, Antonio, A. DE GASPERIS, de Angelis, Costantino, Wabnitz, Stefan, DE ANGELIS C, Lombardo, Sara, S. LOMBARDO, CONFORTI M, DE GASPERIS, Antonio, Baronio, Fabio, Matteo Conforti, BARONIO F, Stefan Wabnitz, Sara Lombardo, Costantino De, Conforti, Matteo, Fabio Baronio, Antonio Degasperis   +17 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

基于Pro/E的锥蜗轮参数化设计建模

Jixie chuandong, 2012
Spiroid gear transmission is the space cross-axis transmission.The spiroid gear has the complex spatial tooth surface.It’s difficult to calculate and modeling.A new method about gear tooth surface modeling and parametric design is approached,the ...
赵泽敏, 范元勋, 於陈程, 方忠坚   +3 more
doaj  

An Efficient Parametric Modeling, Evaluation and Optimization Strategy for Aerodynamic Configuration Design of eVTOL Aircraft

Aerospace Research Communications
Traditional aerodynamic design faces significant limitations in modeling and computational efficiency during conceptual design stage. A phased collaborative aerodynamic design strategy for eVTOL aircraft was established, by combining the OpenVSP platform
Yiming Du, Zehao Liu, Meizhu Shen, Jiang Wu, Kexin Zhang, Chuanye Jiang, Jiale Zhong   +6 more
doaj   +1 more source