Results 81 to 90 of about 2,932,686 (296)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

A Component-based Software Development and Execution Framework for CAx Applications

open access: yesActa Polytechnica, 2004
Digitalization of the manufacturing process and technologies is regarded as the key to increased competitive ability. The MZ-Platform infrastructure is a component-based software development framework, designed for supporting enterprises to enhance ...
N. Matsuki, H. Tokunaga, H. Sawada
doaj  

A Rapid Method of Integrated Aeropropulsive Analysis for the Conceptual Design of Airbreathing Hypersonic Aircraft

open access: yesAerospace
A special feature of airbreathing hypersonic aircraft is the complex coupling between aerodynamic and propulsive performances. This study presents a rapid analysis methodology for the integration of these two critical aspects in the conceptual design of ...
Yalin Dai   +4 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Multi-objective optimization and characteristic analysis of contra-rotating fan double-row blades coupling

open access: yesMeikuang Anquan
To enhance the aerodynamic performance of contra-rotating fan and ensure the safe working environment of mine, based on feedforward neural network agent model and genetic algorithm, the multi-objective optimization of contra-rotating fan double-row ...
Xinyu ZHANG, Hua JIANG, Wuqi GONG
doaj   +1 more source

The parametric propagation in underwater acoustics : experimental results [PDF]

open access: yes, 2012
In underwater acoustics, detection of buried objects in sediments (cables, mines, . . . ) is a complex problem. Indeed, in order to ensure sufficient penetration depth in marine sediments, low frequencies have to be used, implying a low resolution.
BOUTTARD, Etienne   +6 more
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Resistance welding parametric modeling based on CATIA CAA

open access: yesJournal of Hebei University of Science and Technology, 2019
There′re numbers of welding spots and types in vehicle seat framework (VSF) and high welding quality requirement, while commercial CAD weld design has low efficiency and cannot satisfy customers′ requirement, so it′s urgent to realize automated ...
Huawei CHEN   +3 more
doaj   +1 more source

Option data and modeling BSM implied volatility [PDF]

open access: yes
This contribution to the Handbook of Computational Finance, Springer-Verlag, gives an overview on modeling implied volatility data. After introducing the concept of Black-Scholes-Merton implied volatility (IV), the empirical stylized facts of IV data are
Matthias Fengler
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

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