Results 81 to 90 of about 24,899,885 (305)
AerospaceA special feature of airbreathing hypersonic aircraft is the complex coupling between aerodynamic and propulsive performances. This study presents a rapid analysis methodology for the integration of these two critical aspects in the conceptual design of ...
Yalin Dai +4 more
doaj +1 more source
BIM AND GIS: WHEN PARAMETRIC MODELING MEETS GEOSPATIAL DATA
, 2017 . Geospatial data have a crucial role in several projects related to infrastructures and land management. GIS software are able to perform advanced geospatial analyses, but they lack several instruments and tools for parametric modelling typically ...
L. Barazzetti, F. Banfi
semanticscholar +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Meikuang AnquanTo enhance the aerodynamic performance of contra-rotating fan and ensure the safe working environment of mine, based on feedforward neural network agent model and genetic algorithm, the multi-objective optimization of contra-rotating fan double-row ...
Xinyu ZHANG, Hua JIANG, Wuqi GONG
doaj +1 more source
Resistance welding parametric modeling based on CATIA CAA
Journal of Hebei University of Science and Technology, 2019 There′re numbers of welding spots and types in vehicle seat framework (VSF) and high welding quality requirement, while commercial CAD weld design has low efficiency and cannot satisfy customers′ requirement, so it′s urgent to realize automated ...
Huawei CHEN +3 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Applied Sciences, 2020 Building information modeling (BIM) has been widely applied in conjunction with the industry foundation class (IFC) for buildings and infrastructure such as railways.
Tae Ho Kwon +3 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
flexsurv: A Platform for Parametric Survival Modeling in R
Journal of Statistical Software, 2016 flexsurv is an R package for fully-parametric modeling of survival data. Any parametric time-to-event distribution may be fitted if the user supplies a probability density or hazard function, and ideally also their cumulative versions.
C. Jackson
semanticscholar +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source