Results 81 to 90 of about 2,932,686 (296)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
A Component-based Software Development and Execution Framework for CAx Applications
Digitalization of the manufacturing process and technologies is regarded as the key to increased competitive ability. The MZ-Platform infrastructure is a component-based software development framework, designed for supporting enterprises to enhance ...
N. Matsuki, H. Tokunaga, H. Sawada
doaj
A special feature of airbreathing hypersonic aircraft is the complex coupling between aerodynamic and propulsive performances. This study presents a rapid analysis methodology for the integration of these two critical aspects in the conceptual design of ...
Yalin Dai +4 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
To enhance the aerodynamic performance of contra-rotating fan and ensure the safe working environment of mine, based on feedforward neural network agent model and genetic algorithm, the multi-objective optimization of contra-rotating fan double-row ...
Xinyu ZHANG, Hua JIANG, Wuqi GONG
doaj +1 more source
The parametric propagation in underwater acoustics : experimental results [PDF]
In underwater acoustics, detection of buried objects in sediments (cables, mines, . . . ) is a complex problem. Indeed, in order to ensure sufficient penetration depth in marine sediments, low frequencies have to be used, implying a low resolution.
BOUTTARD, Etienne +6 more
core
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Resistance welding parametric modeling based on CATIA CAA
There′re numbers of welding spots and types in vehicle seat framework (VSF) and high welding quality requirement, while commercial CAD weld design has low efficiency and cannot satisfy customers′ requirement, so it′s urgent to realize automated ...
Huawei CHEN +3 more
doaj +1 more source
Option data and modeling BSM implied volatility [PDF]
This contribution to the Handbook of Computational Finance, Springer-Verlag, gives an overview on modeling implied volatility data. After introducing the concept of Black-Scholes-Merton implied volatility (IV), the empirical stylized facts of IV data are
Matthias Fengler
core
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source

