Results 71 to 80 of about 2,932,686 (296)
Micromachines, 2020 The rational-based neuro-transfer function (neuro-TF) method is a popular method for parametric modeling of electromagnetic (EM) behavior of microwave components.
Zhihao Zhao +6 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Parametric model-based clustering [PDF]
SPIE Proceedings, 2005 Parametric, model-based algorithms learn generative models from the data, with each model corresponding to one particular cluster. Accordingly, the model-based partitional algorithm will select the most suitable model for any data object (Clustering step}, and will recompute parametric models using data specifically from the corresponding clusters ...
Nikulin, Vladimir, Smola, Alexander
openaire +4 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
MLLMto3D: An MCP-Driven Closed-Loop Framework for Architectural 3D Generation
BuildingsMultimodal large language models can read architectural images and design instructions but they still struggle to turn architectural rules into editable, executable models in professional modeling environments.
Dong Yao, Bingcheng He, Xiaoxi Zhao
doaj +1 more source
GDP nowcasting with ragged-edge data: a semi-parametric modeling [PDF]
This paper formalizes the process of forecasting unbalanced monthly datasets in order to obtain robust nowcasts and forecasts of quarterly gross domestic product (GDP) growth rate through a semi-parametric modeling.
Patrick Rakotomarolahy +2 more
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
SensorsMonitoring a deep geological repository for radioactive waste during the operational phases relies on a combination of fit-for-purpose numerical simulations and online sensor measurements, both producing complementary massive data, which can then be ...
David Muñoz +4 more
doaj +1 more source